Evidence map›Paper›PMID 33963422›Full record

ArticleJournal of digital imaging2021

Improving the Subtype Classification of Non-small Cell Lung Cancer by Elastic Deformation Based Machine Learning.

Yang Gao, Fan Song, Peng Zhang, Jian Liu, Jingjing Cui, Yingying Ma, Guanglei Zhang, Jianwen Luo

Abstract read
In one paragraph

Article in Journal of digital imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yang GaoDepartment of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China.
Fan SongBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, China.
Peng ZhangBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, China.
Jian LiuBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, China.
Jingjing CuiBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, China.
Yingying MaMedical Engineering Management Office, Shandong Provincial Hospital Affiliated To Shandong University, Jinan, 250021, China.
Guanglei ZhangBeijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, 100083, China. guangleizhang@buaa.edu.cn.
Jianwen LuoDepartment of Biomedical Engineering, School of Medicine, Tsinghua University, Beijing, China. luo_jianwen@tsinghua.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Non-invasive image-based machine learning models have been used to classify subtypes of non-small cell lung cancer (NSCLC). However, the classification performance is limited by the dataset size, because insufficient data cannot fully represent the characteristics of the tumor lesions. In this work, a data augmentation method named elastic deformation is proposed to artificially enlarge the image dataset of NSCLC patients with two subtypes (squamous cell carcinoma and large cell carcinoma) of 3158 images. Elastic deformation effectively expanded the dataset by generating new images, in which tumor lesions go through elastic shape transformation. To evaluate the proposed method, two classification models were trained on the original and augmented dataset, respectively. Using augmented dataset for training significantly increased classification metrics including area under the curve (AUC) values of receiver operating characteristics (ROC) curves, accuracy, sensitivity, specificity, and f

Indexed as

Carcinoma, Non-Small-Cell LungLung NeoplasmsHumansMachine LearningRetrospective StudiesTomography, X-Ray ComputedData augmentationElastic deformationMachine learningNon-small cell lung cancer (NSCLC)RadiomicsSubtype classification

Identifiers

PMID33963422
PMCPMC8329138

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.