Evidence map›Paper›PMID 33963421›Full record

ArticleJournal of digital imaging2021

Rapid Assessment of Acute Ischemic Stroke by Computed Tomography Using Deep Convolutional Neural Networks.

Chung-Ming Lo, Peng-Hsiang Hung, Daw-Tung Lin

Abstract read
In one paragraph

Article in Journal of digital imaging, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Chung-Ming LoGraduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan.
Peng-Hsiang Hung *Graduate Institute of Biomedical Informatics, College of Medical Science and Technology, Taipei Medical University, Taipei, Taiwan. sacbusec175@gmail.com.ORCID 0000-0003-1070-432X
Daw-Tung Lin *Department of Computer Science and Information Engineering, National Taipei University, 151 University Rd., Taipei, 237, Sanshia, Taiwan. dalton@mail.ntpu.edu.tw.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Acute stroke is one of the leading causes of disability and death worldwide. Regarding clinical diagnoses, a rapid and accurate procedure is necessary for patients suffering from acute stroke. This study proposes an automatic identification scheme for acute ischemic stroke using deep convolutional neural networks (DCNNs) based on non-contrast computed tomographic (NCCT) images. Our image database for the classification model was composed of 1254 grayscale NCCT images from 96 patients (573 images) with acute ischemic stroke and 121 normal controls (681 images). According to the consensus of critical stroke findings by two neuroradiologists, a gold standard was established and used to train the proposed DCNN using machine-generated image features. Including the earliest DCNN, AlexNet, the popular Inception-v3, and ResNet-101 were proposed. To train the limited data size, transfer learning with ImageNet parameters was also used. The established models were evaluated by tenfold cross-validation and tested on an independent dataset containing 50 patients with acute ischemic stroke (108 images) and 58 normal controls (117 images) from another institution. AlexNet without pretrained parameters achieved an accuracy of 97.12%, a sensitivity of 98.11%, a specificity of 96.08%, and an area under the receiver operating characteristic curve (AUC) of 0.9927. Using transfer learning, transferred AlexNet, transferred Inception-v3, and transferred ResNet-101 achieved accuracies between 90.49 and 95.49%. Tested with a dataset from another institution, AlexNet showed an accuracy of 60.89%, a sensitivity of 18.52%, and a specificity of 100%. Transferred AlexNet, Inception-v3, and ResNet-101 achieved accuracies of 81.77%, 85.78%, and 80.89%, respectively. The proposed DCNN architecture as a computer-aided diagnosis system showed that training from scratch can generate a customized model for a specific scanner, and transfer learning can generate a more generalized model to provide diagnostic suggestions of acute ischemic stroke to radiologists.

Indexed as

Brain IschemiaIschemic StrokeStrokeHumansNeural Networks, ComputerTomography, X-Ray ComputedAcute ischemic strokeComputed tomographyConvolutional neural networks

Identifiers

PMID33963421
PMCPMC8329118

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.