Evidence map›Paper›PMID 33962998›Full record

ReviewEuropean journal of hospital pharmacy : science and practice2023

How can we optimise the pharmaceutical analysis of radiopharmaceutical pediatric prescriptions?

Pauline Leclerc, Solène Marie, Julien Fouque, Madar Olivier, Sandy Blondeel-Gomes

Abstract readReview
In one paragraph

Review in European journal of hospital pharmacy : science and practice, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Pauline LeclercRadio-Pharmacology, Institut Curie, PSL Research University, Paris, France.ORCID 0000-0002-4508-4207
Solène MariePharmacy and Sterilization Department, AP-HP Université Paris Saclay, Hôpital Bicêtre, Le Kremlin-Bicetre, Île-de-France, France.
Julien FouqueRadio-Pharmacology, Institut Curie, Saint Cloud, Paris, France.
Madar OlivierRadio-Pharmacology, Institut Curie, Saint Cloud, Paris, France.
Sandy Blondeel-GomesRadio-Pharmacology, Institut Curie, PSL Research University, Paris, France sandy.blondeel@curie.fr.ORCID 0000-0002-6437-8753

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesIn France, dispensation is defined by the validation of a prescription associated with a pharmaceutical analysis, preparation of medication and provision of information necessary for proper use. There are very few data available in the literature that describe prescription analysis modality in radiopharmacy. The aim was to secure a place for paediatric prescription analysis in radiopharmacy by designing a flow chart validated by experts.

methodsExperts from different disciplines and health setups (ie, public, private) were selected to represent the various paediatric patient care processes. A review of the literature on pharmaceutical analysis and paediatric prescription in radiopharmacy was conducted. A Delphi approach comprising two rounds (Google Form survey) was used to validate the flow chart. Answers were graded according to a nine-point Likert scale for agreement. Open-ended questions allowed experts to comment on the propositions. A consensus between experts was reached if more than 70% of the experts agreed on an item and fewer than 30% disagreed.

resultsSixty-five experts were solicited: two oncopaediatricians, three nuclear medicine physicians, 46 radiopharmacists, three residents in radiopharmacy, one hospital pharmacist, five medical physicists, one pharmacy technician, two X-ray technicians and two patients who are pharmacists. The first round survey included a draft of the flow chart: 31 experts answered (48%). All professional disciplines were represented except pharmacy technician. The second round survey was sent with a new flow chart that had been improved by the experts' comments. After 3 weeks, 18 answers were obtained (28%). After the first round, consensus was obtained for each item. Experts gave a total of 97 comments. The second flow chart had three steps: regulatory aspects, patient data, and radiopharmaceutical data, and it was accompanied by descriptive text explaining the field of application.

conclusionThe resulting flow chart will secure the pharmaceutical analysis step for this special patient population.

Indexed as

PrescriptionsRadiopharmaceuticalsChildHumansRadiopharmaceuticalshospitalnuclear medicinepediatricspharmaceutical preparationspharmacy servicequality of health caretotal quality management

Identifiers

PMID33962998
PMCPMC9811567

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.