Evidence map›Paper›PMID 33962959›Full record

ArticleJournal of clinical microbiology2021

Performance of Three SARS-CoV-2 Immunoassays, Three Rapid Lateral Flow Tests, and a Novel Bead-Based Affinity Surrogate Test for the Detection of SARS-CoV-2 Antibodies in Human Serum.

Manuel Krone, Julia Gütling, Johannes Wagener, Thiên-Trí Lâm, Christoph Schoen, Ulrich Vogel, August Stich, Florian Wedekink, Jörg Wischhusen, Thomas Kerkau and 7 more

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.2field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 2 countries.

Manuel KroneInstitute for Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
Julia GütlingInstitute for Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
Johannes WagenerInstitute for Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
Thiên-Trí LâmInstitute for Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
Christoph SchoenInstitute for Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
Ulrich VogelInstitute for Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
August StichDepartment of Tropical Medicine, Missioklinik, Klinikum Wuerzburg Mitte, Wuerzburg, Germany.
Florian WedekinkDepartment of Gynecology, Section for Experimental Tumor Immunology, University Hospital Wuerzburg, Wuerzburg, Germany.
Jörg WischhusenDepartment of Gynecology, Section for Experimental Tumor Immunology, University Hospital Wuerzburg, Wuerzburg, Germany.
Thomas KerkauInstitute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Niklas BeyersdorfInstitute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Silvana KlinglerInstitute of Systems Immunology, University of Wuerzburg, Wuerzburg, Germany.
Simone BackesInstitute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Lars DölkenInstitute for Virology and Immunobiology, University of Wuerzburg, Wuerzburg, Germany.
Georg GasteigerInstitute of Systems Immunology, University of Wuerzburg, Wuerzburg, Germany.
Oliver KurzaiInstitute for Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
Alexandra Schubert-UnkmeirInstitute for Hygiene and Microbiology, University of Wuerzburg, Wuerzburg, Germany.
University of Würzburg · DEUniversitätsklinikum Würzburg · DEKlinikum Würzburg Mitte · DETrinity College Dublin · IE

Funding

Bundesministerium für Bildung und Forschung (BMBF) grant-No 03COV26A
6 · The paper itself

Abstract

For the control of immunity in COVID-19 survivors and vaccinated subjects, there is an urgent need for reliable and rapid serological assays. Based on samples from 63 COVID-19 survivors up to 7 months after symptom onset, and on 50 serum samples taken before the beginning of the pandemic, we compared the performances of three commercial immunoassays for the detection of SARS-CoV-2 IgA and IgG antibodies (Euroimmun SARS-COV-2 IgA/IgG, Mikrogen

Indexed as

COVID-19SARS-CoV-2Antibodies, ViralHumansImmunoassayImmunoglobulin MPandemicsSensitivity and SpecificityAntibodies, ViralImmunoglobulin MCOVID-19ELISAflow cytometry bead-based surrogate testlateral flow assayplaque-reduction neutralization testSARS-CoV-2

Identifiers

PMID33962959
PMCPMC8373215
OpenAlexW3128639708

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.