Evidence map›Paper›PMID 33962613›Full record

ArticleBMC musculoskeletal disorders2021

Tributyltin perturbs femoral cortical architecture and polar moment of inertia in rat.

Mingjun Li, Dong Cheng, Hui Li, Wenhuan Yao, Dongmei Guo, Shu'e Wang, Jiliang Si

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC musculoskeletal disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mingjun LiDepartment of Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 Wenhua Xi Lu, Jinan, 250012, Shandong, China.
Dong ChengDepartment of Toxicology, Shandong Center for Disease Control and Prevention, Jinan, China.
Hui LiDepartment of Toxicology, Shandong Center for Disease Control and Prevention, Jinan, China.
Wenhuan YaoDepartment of Toxicology, Shandong Center for Disease Control and Prevention, Jinan, China.
Dongmei GuoDepartment of Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 Wenhua Xi Lu, Jinan, 250012, Shandong, China.
Shu'e WangDepartment of Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 Wenhua Xi Lu, Jinan, 250012, Shandong, China.
Jiliang SiDepartment of Environmental Health, School of Public Health, Cheeloo College of Medicine, Shandong University, 44 Wenhua Xi Lu, Jinan, 250012, Shandong, China. sjlsdu@sdu.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTributyltin, a well-known endocrine disruptor, is widely used in agriculture and industry. Previous studies have shown that tributyltin could cause deleterious effects on bone health by impairing the adipo-osteogenic balance in bone marrow.

methodsTo investigate further the effects of tributyltin on bone, weaned male SD rats were treated with tributyltin (0.5, 5 or 50 μg·kg

resultsMicro-computed tomography analysis revealed that treatment with 50 μg·kg

conclusionsExposure to a low dose of tributyltin from the prepubertal to adult stage produced adverse effects on skeletal architecture and strength.

Indexed as

Bone DensityFemurAnimalsMaleRatsRats, Sprague-DawleyTrialkyltin CompoundsX-Ray MicrotomographyTrialkyltin CompoundstributyltinAdipogenesisBone geometryMicro-computed tomographyOsteogenesisPolar moment of inertiaTributyltin

Identifiers

PMID33962613
PMCPMC8106170

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.