Evidence map›Paper›PMID 33962531›Full record

ArticleAutism : the international journal of research and practice2021

The Early Screening for Autism and Communication Disorders: Field-testing an autism-specific screening tool for children 12 to 36 months of age.

Amy M Wetherby, Whitney Guthrie, Jessica L Hooker, Abigail Delehanty, Taylor N Day, Juliann Woods, Karen Pierce, Stacy S Manwaring, Audrey Thurm, Sally Ozonoff and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Autism : the international journal of research and practice, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 31 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. The earlier the better: An RCT of treatment timing effects for toddlers on the autism spectrum.Autism : the international journal of research and practice · 2023
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Prenatal exposure to pesticide residues in the diet in association with child autism-related traits: Results from the EARLI study.Autism research : official journal of the International Society for Autism Research · 2022
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 1 country.

Amy M WetherbyFlorida State University, USA.ORCID 0000-0001-9072-8537
Whitney GuthrieUniversity of Pennsylvania, USA.
Jessica L HookerFlorida State University, USA.ORCID 0000-0002-6219-5005
Abigail DelehantyDuquesne University, USA.
Taylor N DayFlorida State University, USA.
Juliann WoodsFlorida State University, USA.
Karen PierceUniversity of California, San Diego, USA.
Stacy S ManwaringThe University of Utah, USA.
Audrey ThurmNational Institutes of Health, USA.
Sally OzonoffUniversity of California, Davis, USA.
Eva PetkovaNew York University, USA.
Catherine LordUniversity of California, Los Angeles, USA.ORCID 0000-0001-5633-1253
Florida State University · USCalifornia University of Pennsylvania · USDuquesne University · USNational Institutes of Health · USNew York University · USUniversity of California, Davis · USUniversity of California, Los Angeles · USUniversity of California San Diego · USUniversity of Utah · US

Funding

Clinical and Behavioral Phenotyping of Autism and Related DisordersZIAMH002868 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI SWEDO, SUSAN · 2009 to 2017
$17.8M
Neurodevelopmental and Behavioral Phenotyping ZICMH002961 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI THURM, AUDREY · 2017 to 2025
$12.6M
Smart Early Screening for Autism and Communication Disorders in Primary CareR01HD078410 · NICHD · FLORIDA STATE UNIVERSITY · PI WETHERBY, AMY M · 2014 to 2018
$2.5M
Improving and Streamlining Screening and Diagnosis of ASD at 18-24 Months of AgeR01HD065272 · NICHD · FLORIDA STATE UNIVERSITY · PI WETHERBY, AMY M · 2009 to 2010
$1.9M
FIRST WORDS Project: Implementing Surveillance to Determine the Prevalence of ASDU01DD000304 · DD · FLORIDA STATE UNIVERSITY · PI WETHERBY, AMY M · 2007 to 2010
$1.4M
Social Communication Phenotype of ASD in the Second YearR01DC007462 · NIDCD · FLORIDA STATE UNIVERSITY · PI WETHERBY, AMY M · 2006 to 2010
$1.3M
Intramural NIH HHS ZIA MH002868NCBDD CDC HHS U01 DD000304NICHD NIH HHS R01 HD065272NICHD NIH HHS R01 HD078410NIDCD NIH HHS R01 DC007462
6 · The paper itself

Abstract

lay abstractThere is a critical need for accurate screening tools for autism spectrum disorder in very young children so families can access tailored intervention services as early as possible. However, there are few screeners designed for children 18-24 months. Developing screeners that pick up on the signs of autism spectrum disorder in very young children has proved even more challenging. In this study, we examined a new autism-specific parent-report screening tool, the Early Screening for Autism and Communication Disorders for children between 12 and 36 months of age. Field-testing was done in five sites with 471 children screened for communication delays in primary care or referred for familial risk or concern for autism spectrum disorder. The Early Screening for Autism and Communication Disorders was tested in three age groups: 12-17, 18-23, and 24-36 months. A best-estimate diagnosis of autism spectrum disorder, developmental delay, or typical development was made. Analyses examined all 46 items and identified 30 items that best discriminated autism spectrum disorder from the non-spectrum groups. Cutoffs were established for each age group with good sensitivity and specificity. Results provide preliminary support for the accuracy of the Early Screening for Autism and Communication Disorders as an autism-specific screener in children 12-36 months with elevated risk of communication delay or autism spectrum disorder.

Indexed as

Autism Spectrum DisorderAutistic DisorderCommunication DisordersChildChild, PreschoolHumansInfantMass ScreeningSensitivity and Specificityautism spectrum disorderEarly Screening for Autism and Communication Disordersfield-testingscreeningvalidation

Identifiers

PMID33962531
PMCPMC8418999
OpenAlexW3158056127

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.