ArticleThe Lancet. Public health2021
Prevalence and variability of current depressive disorder in 27 European countries: a population-based study.
Article in The Lancet. Public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 144 papers, 6 of them syntheses that pooled it.
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Who cites it
144 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- The Effects of Aerobic and Resistance Exercise on Depression and Anxiety: Systematic Review With Meta-Analysis.International journal of mental health nursing · 2025Pooled it
- Interventions to Foster Mental Health and Reintegration in Individuals Who Are Unemployed: Systematic Review.JMIR public health and surveillance · 2025Pooled it
- Exploring the association between serotonin transporter promoter region methylation levels and depressive symptoms: a systematic review and multi-level meta-analysis.Translational psychiatry · 2025Pooled it
- Oral side effects of fluoxetine in patients with depressive disorder: A systematic review.Medicina oral, patologia oral y cirugia bucal · 2025Pooled it
- Prevalence estimates of major depressive disorder in 27 European countries from the European Health Interview Survey: accounting for imperfect diagnostic accuracy of the PHQ-8.BMJ mental health · 2023Pooled it
- Experiences of treatment-resistant mental health conditions in primary care: a systematic review and thematic synthesis.BMC primary care · 2022Pooled it
- Young adults' access to mental health care: integrating the Primary Care Behavioral Health model into routine care in Sweden.BMC health services research · 2026Trial
- Relationship between dementia diagnostic characteristics and severity of depressive symptoms in a cross-sectional analysis of HOMESIDE baseline data.Scientific reports · 2025Trial
- Fabrication and efficacy evaluation of scopolamine-loaded dissolving microneedle for rapid antidepressant therapy.International journal of pharmaceutics: X · 2026Article
- Working conditions and mental health among doctors and nurses in the European Union, Iceland, and Norway: a cross-sectional survey.The Lancet regional health. Europe · 2026Article
- Desvenlafaxine as a Potential First-Line Treatment for Major Depressive Disorder: A Comprehensive Review and Consensus-Based Clinical Perspective on Efficacy, Safety and Patient Selection Profiles.Clinical drug investigation · 2026Review
- Clinicians' practices and attitudes toward depression assessment: a cross-sectional survey study.BMC psychology · 2026Article
- Psychological interventions for depression during post-acute inpatient rehabilitation after traumatic or non-traumatic spinal injury: a matched-case control study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026Observational
- Article
- Sex differences in familial risk and genetic components of suicide attempts: a register-based cohort study in Sweden.BMJ mental health · 2026Article
- Association between the condition of living alone and the presence of depressive symptoms in adults in Peru: an analysis of nationally representative survey data.Journal of preventive medicine and hygiene · 2026Observational
- Unraveling the role of IL-17 signaling pathway in breast cancer-related depression: insights from in vivo/in vitro models and transcriptomic analysis.Functional & integrative genomics · 2026Article
- Influence ofPharmaceuticals (Basel, Switzerland) · 2026Article
- Trends in depression in the European population aged 50 years and older by geographic region.American journal of epidemiology · 2026Article
- Revisiting the factor structure of the EURO-D, a depressive symptomatology scale: An exploratory graph analysis in 26 European countries.Global mental health (Cambridge, England) · 2026Article
84 more citing papers are in PubMed but not listed here.
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Funding
Abstract
backgroundWe aimed to estimate the prevalence of current depressive disorder in 27 European countries, and to explore differences in prevalence between European countries and by gender.
methodsIn this population-based study, we analysed data from respondents living in 27 European countries who were included in the second wave of the European Health Interview Survey, collected between 2013 and 2015. We assessed the prevalence of current depressive disorder using the eight-item Patient Health Questionnaire (PHQ-8), with depressive disorder defined as a PHQ-8 score of 10 or higher. Prevalence estimates and 95% CIs were calculated for all 27 countries overall and for each country individually. We assessed variation in prevalence (country vs the rest of Europe) using crude and adjusted prevalence ratios obtained from negative binomial regression models. We did all analyses for the total sample and stratified by gender.
findingsOur analysis sample comprised 258 888 individuals, of whom 117 310 (weighted proportion 47·8%) were men and 141 578 (52·2%) were women. The overall prevalence of current depressive disorder was 6·38% (95% CI 6·24-6·52) with important variation across countries, ranging from 2·58% (2·14-3·02) in the Czech Republic to 10·33% (9·33-11·32) in Iceland. Prevalence was higher in women (7·74% [7·53-7·95]) than in men (4·89% [4·71-5·08]), with clear gender differences for all countries except Finland and Croatia. Compared with the other European countries in our sample, those with the highest adjusted prevalence ratios were Germany (1·80 [1·71-1·89]) and Luxembourg (1·50 [1·35-1·66]), and those with the lowest adjusted prevalence ratios were Slovakia (0·28 [0·24-0·33]) and the Czech Republic (0·32 [0·27-0·38]).
interpretationDepressive disorders, although common across Europe, vary substantially in prevalence between countries. These results could be a baseline for monitoring the prevalence of current depressive disorder both at a country level in Europe and for planning health-care resources and services.
fundingUK Medical Research Council and CIBER Epidemiology and Public Health (CIBERESP).
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