Evidence map›Paper›PMID 33961770›Full record

ArticleCell stem cell2021

3D iPSC modeling of the retinal pigment epithelium-choriocapillaris complex identifies factors involved in the pathology of macular degeneration.

Kannan V Manian, Chad A Galloway, Sonal Dalvi, Anthony A Emanuel, Jared A Mereness, Whitney Black, Lauren Winschel, Celia Soto, Yiming Li, Yuanhui Song and 9 more

Abstract readPublished Erratum
In one paragraph

Article in Cell stem cell, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

19 authors.

Kannan V Manian
Chad A Galloway
Sonal Dalvi
Anthony A Emanuel
Jared A Mereness
Whitney Black
Lauren Winschel
Celia Soto
Yiming Li
Yuanhui Song
William DeMaria
Akhilesh Kumar
Igor Slukvin
Michael P Schwartz
William L Murphy
Bela Anand-Apte
Mina Chung
Danielle S W Benoit
Ruchira Singh

Funding

RESOURCE/SERVICE CORE C - MOLECULAR INFORMATICS MODULEP30EY025585 · NEI · CLEVELAND CLINIC LERNER COM-CWRU · PI BELA ANAND-APTE · 2016 to 2026
$7.7M
Harnessing human brain and liver microphysiological systems for testing therapeutics for metastatic melanomaU01TR002383 · NCATS · VANDERBILT UNIVERSITY · PI MURPHY, WILLIAM L., TAYLOR, D. LANSING · 2018 to 2022
$7.6M
Tissue Engineering Strategies to Revitalize Bone AllograftsR01AR064200 · NIAMS · UNIVERSITY OF ROCHESTER · PI Danielle S. Benoit · 2013 to 2026
$4.0M
Regulation of Choroidal Neovascularization in Sorsby's Fundus DystrophyR01EY027083 · NEI · CLEVELAND CLINIC LERNER COM-CWRU · PI ANAND-APTE, BELA · 2017 to 2024
$4.0M
Delineating the role of TIMP3 in macular degenerationR01EY028167 · NEI · UNIVERSITY OF ROCHESTER · PI SINGH, RUCHIRA · 2017 to 2025
$3.8M
Engineered salivary gland tissue chips (Administrative Supplement)UH3DE027695 · NIDCR · UNIVERSITY OF ROCHESTER · PI BENOIT, DANIELLE S., DELOUISE, LISA A · 2019 to 2021
$3.0M
Determining the role of CLN3 in the eyeR01EY030183 · NEI · UNIVERSITY OF ROCHESTER · PI SINGH, RUCHIRA · 2019 to 2022
$2.0M
A Neurovascular Microphysiological SystemR01NS109427 · NINDS · UNIVERSITY OF WISCONSIN-MADISON · PI MURPHY, WILLIAM L. · 2019 to 2023
$1.7M
hiPSC-derived tissue mimetics of the retina blood barrierR21EY030817 · NEI · UNIVERSITY OF ROCHESTER · PI BENOIT, DANIELLE S., SINGH, RUCHIRA · 2020 to 2021
$417k
NCATS NIH HHS U01 TR002383NEI NIH HHS P30 EY025585NEI NIH HHS R01 EY027083NEI NIH HHS R01 EY028167NEI NIH HHS R01 EY030183NEI NIH HHS R21 EY030817NIAMS NIH HHS R01 AR064200NIDCR NIH HHS UH3 DE027695NINDS NIH HHS R01 NS109427
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID33961770
PMCPMC8532521

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.