Evidence map›Paper›PMID 33961404›Full record

ArticleACS nano2021

Förster Resonance Energy Transfer Nanoplatform Based on Recognition-Induced Fusion/Fission of DNA Mixed Micelles for Nucleic Acid Sensing.

Setareh Vafaei, Francia Allabush, Seyed R Tabaei, Louise Male, Timothy R Dafforn, James H R Tucker, Paula M Mendes

Abstract read
In one paragraph

Article in ACS nano, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Enhanced light harvesting through efficient energy transfer in a pluronic co-polymer scaffolded blend of donor dyes and plasmonic Au-MoSPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Setareh VafaeiSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
Francia AllabushSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
Seyed R TabaeiSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.ORCID 0000-0002-2857-786X
Louise MaleSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.ORCID 0000-0002-8295-2528
Timothy R DaffornSchool of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.
James H R TuckerSchool of Chemistry, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.ORCID 0000-0001-7645-0815
Paula M MendesSchool of Chemical Engineering, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom.ORCID 0000-0001-6937-7293

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The dynamic nature of micellar nanostructures is employed to form a self-assembled Förster resonance energy transfer (FRET) nanoplatform for enhanced sensing of DNA. The platform consists of lipid oligonucleotide FRET probes incorporated into micellar scaffolds, where single recognition events result in fusion and fission of DNA mixed micelles, triggering the fluorescence response of multiple rather than a single FRET pair. In comparison to conventional FRET substrates where a single donor interacts with a single acceptor, the micellar multiplex FRET system showed ∼20- and ∼3-fold enhancements in the limit of detection and FRET efficiency, respectively. This supramolecular signal amplification approach could potentially be used to improve FRET-based diagnostic assays of nucleic acid and non-DNA based targets.

Indexed as

NanostructuresNucleic AcidsDNAFluorescence Resonance Energy TransferMicellesDNAMicellesNucleic AcidsDNA sensingFRETlipid oligonucleotide conjugatesmicellesignal enhancement

Identifiers

PMID33961404
PMCPMC8158853

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.