Evidence map›Paper›PMID 33961402›Full record

ArticleBiochemistry2021

A pH Switch Controls Zinc Binding in Tomato Copper-Zinc Superoxide Dismutase.

Kevin W Sea, Alexander B Taylor, Susan T Thomas, Amir Liba, Isabelle B Bergman, Stephen P Holloway, Xiaohang Cao, Edith B Gralla, Joan S Valentine, P John Hart and 1 more

Open access · greenAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Biochemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 96% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Kevin W SeaDepartment of Agriculture and Natural Resources, Santa Rosa Junior College, Santa Rosa, California 95401, United States.
Alexander B TaylorDepartment of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States.ORCID 0000-0003-3517-6033
Susan T ThomasDepartment of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States.
Amir LibaDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.
Isabelle B BergmanDepartment of Biological Sciences, St. Mary's University, San Antonio, Texas 78228, United States.
Stephen P HollowayDepartment of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States.
Xiaohang CaoDepartment of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States.
Edith B GrallaDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.
Joan S ValentineDepartment of Chemistry and Biochemistry, University of California, Los Angeles, Los Angeles, California 90095, United States.
P John HartDepartment of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States.
Ahmad GalaleldeenDepartment of Biochemistry and Structural Biology, The University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, San Antonio, Texas 78229, United States.ORCID 0000-0003-1160-6908
The University of Texas Health Science Center at San Antonio · USUniversity of California, Los Angeles · USSanta Rosa Junior College · USSt. Mary's University, Texas · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Lei Zheng · 1991 to 2026
$59.1M
Testing Hypotheses by Site Directed Mutagenesis of SOD1P01NS049134 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI BORCHELT, DAVID R · 2005 to 2014
$10.9M
X RAY STUDY OF DIOXYGEN CARRIER MODELS OF OXYHEMOPROTEINS06GM008073 · NIGMS · UNIVERSITY OF HAWAII AT HILO · PI BROWN, SUSAN GAY · 1989 to 2007
$6.4M
UNDERGRADUATE STUDENT TRAINING IN ACADEMIC RESEARCHT34GM008073 · NIGMS · ST. MARY'S UNIVERSITY · PI CONTRERAS-SHANNON, VERONICA E · 1985 to 2022
$5.7M
X-RAY STUDIES OF SOD IN AMYOTROPHIC LATERAL SCLEROSISR01NS039112 · NINDS · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI HART, PETER JOHN · 2000 to 2010
$2.7M
NCI NIH HHS P30 CA054174NIGMS NIH HHS S06 GM008073NIGMS NIH HHS T34 GM008073NINDS NIH HHS P01 NS049134NINDS NIH HHS R01 NS039112
6 · The paper itself

Abstract

Copper-zinc superoxide dismutase (SOD1) is a major antioxidant metalloenzyme that protects cells from oxidative damage by superoxide anions (O

Indexed as

Binding SitesChelating AgentsCopperDisulfidesHydrogen-Ion ConcentrationLigandsMetalsMolecular ChaperonesProtein BindingProtein ConformationSolanum lycopersicumSuperoxide DismutaseSuperoxide Dismutase-1SuperoxidesZincChelating AgentsCopperDisulfidesLigandsMetalsMolecular ChaperonesSuperoxide DismutaseSuperoxide Dismutase-1SuperoxidesZinc

Identifiers

PMID33961402
PMCPMC8754426
OpenAlexW3159266807

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.