Evidence map›Paper›PMID 33961394›Full record

ArticleAnalytical chemistry2021

PDMS Curing Inhibition on 3D-Printed Molds: Why? Also, How to Avoid It?

Bastien Venzac, Shanliang Deng, Ziad Mahmoud, Aufried Lenferink, Aurélie Costa, Fabrice Bray, Cees Otto, Christian Rolando, Séverine Le Gac

Abstract read
In one paragraph

Article in Analytical chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed.

  1. Article
  2. Tailoring Superwettability Through Bioinspired Reentrant Microstructures.Advanced materials (Deerfield Beach, Fla.) · 2026
    Review
  3. Article
  4. Article
  5. Article
  6. Copying a soft lithography master mold using an inexpensive, hobby-use UV-curable resin.Analytical sciences : the international journal of the Japan Society for Analytical Chemistry · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Review
  16. Augmented 3D Printing for Multiscale Microphysiological Systems.Small (Weinheim an der Bergstrasse, Germany) · 2025
    Review
  17. Article
  18. Article
  19. Article
  20. Review

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bastien VenzacApplied Microfluidics for BioEngineering Research, MESA+ Institute for Nanotechnology & TechMed Centre, University of Twente, 7500AE Enschede, The Netherlands.
Shanliang DengApplied Microfluidics for BioEngineering Research, MESA+ Institute for Nanotechnology & TechMed Centre, University of Twente, 7500AE Enschede, The Netherlands.
Ziad MahmoudUniversité Lille, CNRS, USR 3290, MSAP, Miniaturisation pour la Synthèse l'Analyse et la Protéomique, 59000 Lille, France.ORCID 0000-0002-5563-0558
Aufried LenferinkMedical Cell BioPhysics, TechMed Centre, University of Twente, 7500AE Enschede, The Netherlands.
Aurélie CostaUniversité Lille, CNRS, USR 3290, MSAP, Miniaturisation pour la Synthèse l'Analyse et la Protéomique, 59000 Lille, France.
Fabrice BrayUniversité Lille, CNRS, USR 3290, MSAP, Miniaturisation pour la Synthèse l'Analyse et la Protéomique, 59000 Lille, France.
Cees OttoMedical Cell BioPhysics, TechMed Centre, University of Twente, 7500AE Enschede, The Netherlands.
Christian RolandoUniversité Lille, CNRS, USR 3290, MSAP, Miniaturisation pour la Synthèse l'Analyse et la Protéomique, 59000 Lille, France.ORCID 0000-0002-3266-8860
Séverine Le GacApplied Microfluidics for BioEngineering Research, MESA+ Institute for Nanotechnology & TechMed Centre, University of Twente, 7500AE Enschede, The Netherlands.ORCID 0000-0002-4546-6184

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three-dimensional (3D)-printing techniques such as stereolithography (SLA) are currently gaining momentum for the production of miniaturized analytical devices and molds for soft lithography. However, most commercially available SLA resins inhibit polydimethylsiloxane (PDMS) curing, impeding reliable replication of the 3D-printed structures in this elastomeric material. Here, we report a systematic study, using 16 commercial resins, to identify a fast and straightforward treatment of 3D-printed structures and to support accurate PDMS replication using UV and/or thermal post-curing. In-depth analysis using Raman spectroscopy, nuclear magnetic resonance, and high-resolution mass spectrometry revealed that phosphine oxide-based photo-initiators, leaching out of the 3D-printed structures, are poisoning the Pt-based PDMS catalyst. Yet, upon UV and/or thermal treatments, photo-initiators were both eliminated and recombined into high molecular weight species that were sequestered in the molds.

Indexed as

DimethylpolysiloxanesPrinting, Three-DimensionalDimethylpolysiloxanes

Identifiers

PMID33961394
PMCPMC8153387

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.