Evidence map›Paper›PMID 33961200›Full record

ArticleSleep & breathing = Schlaf & Atmung2022

Use of average volume-assured pressure support as a therapeutic option in patients with central sleep apnea syndrome.

John Mario Levri, Naomitsu Watanabe, Victor T Peng, Steven M Scharf, Montserrat Diaz-Abad

Abstract read
PubMed Publisher
In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. 3-minute central apneas: enhanced expiratory rebreathing space to the rescue.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

John Mario LevriSleep Disorders Center, University of Maryland Medical Center, 100 North Green Street Room 204, Baltimore, MD, 21201, USA. johnlevri@gmail.com.ORCID 0000-0002-4691-0742
Naomitsu WatanabeSleep Disorders Center, University of Maryland Medical Center, 100 North Green Street Room 204, Baltimore, MD, 21201, USA.
Victor T PengDepartment of Medicine, University of Maryland Medical Center Midtown Campus, Baltimore, MD, USA.
Steven M ScharfSleep Disorders Center, Division of Pulmonary and Critical Care, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
Montserrat Diaz-AbadSleep Disorders Center, Division of Pulmonary and Critical Care, Department of Medicine, University of Maryland School of Medicine, Baltimore, MD, USA.
University of Maryland, Baltimore · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCentral sleep apnea (CSA) syndrome commonly occurs with other medical conditions such as congestive heart failure, opiate use, and brainstem disorders. Various treatment modalities have been used with varied effectiveness in an attempt to improve ventilation and reduce the apnea-hypopnea index (AHI) in patients with CSA. This study evaluated whether or not a bilevel positive airway pressure mode of noninvasive ventilation, average volume-assured pressure support (AVAPS) is effective in treating CSA.

methodsThis was a retrospective review of patients with CSA who underwent AVAPS titration studies at our institution. We included patients with CSA with apnea-hypopnea index (events/hour) (AHI) ≥ 15, and examined the effectiveness of AVAPS in reducing AHI, improving oxygenation parameters, and improving sleep architecture.

resultsThere were 12 patients, with mean age 62.8 ± 11.5 years, body mass index (BMI) 33.5 ± 4.7 kg/m

conclusionAVAPS is an effective mode of treating CSA in a significant proportion of patients. More studies are needed to confirm these findings and determine what factors are associated with response to therapy.

Indexed as

Continuous Positive Airway PressureNoninvasive VentilationAgedFemaleHumansMaleMiddle AgedRetrospective StudiesSleep Apnea, CentralTreatment OutcomeAVAPSCentral sleep apneaCongestive heart failure (CHF)Noninvasive ventilationOpiateTherapy

Identifiers

PMID33961200
OpenAlexW3158962649

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.