Evidence map›Paper›PMID 33961137›Full record

ReviewCurrent cardiology reports2021

Impact of Early Blood Pressure Lowering in Patients Presenting with Acute Ischemic Stroke.

A Maud, G J Rodriguez, A Vellipuram, F Sheriff, M Ghatali, V Gupta, R Khatri, S Cruz-Flores

Open access · hybridAbstract readReview
In one paragraph

Review in Current cardiology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

A MaudDepartment of Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA. alberto.maud@ttuhsc.edu.ORCID http://orcid.org/0000-0001-5576-7717
G J RodriguezDepartment of Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
A VellipuramDepartment of Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
F SheriffDepartment of Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
M GhataliDepartment of Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
V GuptaDepartment of Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
R KhatriDepartment of Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
S Cruz-FloresDepartment of Neurology, Texas Tech University Health Sciences Center El Paso, El Paso, TX, USA.
Texas Tech University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewIn this review article we will discuss the acute hypertensive response in the context of acute ischemic stroke and present the latest evidence-based concepts of the significance and management of the hemodynamic response in acute ischemic stroke. RECENT

findingsAcute hypertensive response is considered a common hemodynamic physiologic response in the early setting of an acute ischemic stroke. The significance of the acute hypertensive response is not entirely well understood. However, in certain types of acute ischemic strokes, the systemic elevation of the blood pressure helps to maintain the collateral blood flow in the penumbral ischemic tissue. The magnitude of the elevation of the systemic blood pressure that contributes to the maintenance of the collateral flow is not well established. The overcorrection of this physiologic hemodynamic response before an effective vessel recanalization takes place can carry a negative impact in the final clinical outcome. The significance of the persistence of the acute hypertensive response after an effective vessel recanalization is poorly understood, and it may negatively affect the final outcome due to reperfusion injury. Acute hypertensive response is considered a common hemodynamic reaction of the cardiovascular system in the context of an acute ischemic stroke. The reaction is particularly common in acute brain embolic occlusion of large intracranial vessels. Its early management before, during, and immediately after arterial reperfusion has a repercussion in the final fate of the ischemic tissue and the clinical outcome.

Indexed as

Brain IschemiaIschemic StrokeStrokeBlood PressureCerebrovascular CirculationHumansAcute ischemic strokeBlood pressureCerebrovascular disease

Identifiers

PMID33961137
PMCPMC8105239
OpenAlexW3158699045

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.