Evidence map›Paper›PMID 33961120›Full record

ReviewCurrent cardiology reports2021

Pheochromocytoma and Paraganglioma in Pregnancy: a New Era.

Lucinda M Gruber, William F Young, Irina Bancos

Abstract readReview
In one paragraph

Review in Current cardiology reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Paraganglioma in Pregnancy with Recurrent Pregnancy Loss: A Case Report.Journal of the ASEAN Federation of Endocrine Societies · 2025
    Article
  4. Article
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  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Rates of Pheochromocytoma/Paraganglioma Screening in At-Risk Populations.The Journal of clinical endocrinology and metabolism · 2023
    Article
  15. Surgical treatment of adrenal tumors during pregnancy.Reviews in endocrine & metabolic disorders · 2023
    Review
  16. Pheochromocytoma in Pregnancy: A Syndromic Association.Journal of obstetrics and gynaecology of India · 2022
    Article
  17. Review
  18. Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Lucinda M GruberDivision of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
William F YoungDivision of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA.
Irina BancosDivision of Endocrinology, Diabetes, Metabolism, and Nutrition, Mayo Clinic, 200 First St. SW, Rochester, MN, 55905, USA. Bancos.Irina@mayo.edu.ORCID http://orcid.org/0000-0001-9332-2524

Funding

Skeletal Consequences of Mild Autonomous Cortisol SecretionK23DK121888 · NIDDK · MAYO CLINIC ROCHESTER · PI BANCOS, IRINA · 2019 to 2022
$630k
NIDDK NIH HHS K23 DK121888NIDDK NIH HHS K23DK121888
6 · The paper itself

Abstract

purpose of reviewPheochromocytoma and paraganglioma (PPGL) in pregnancy is a rare entity and management of these patients is fraught with uncertainty. Our objective is to review current literature and discuss diagnosis and management of these patients. RECENT

findingsOutcomes of PPGL in pregnancy have improved in recent years. The greatest risk for adverse maternal and fetal outcomes is the diagnosis of PPGL after delivery. Alpha- and beta-adrenergic blockade is well tolerated and is associated with less adverse outcomes. Antepartum surgery is not associated with improved maternal or fetal outcomes. Biochemical testing and cross-sectional imaging should be performed prior to conception for patients with a known germline variant associated with PPGL.

conclusionsMedical therapy should be initiated when PPGL is diagnosed in pregnancy. Antepartum surgery should be reserved for special circumstances. Case detection testing in high-risk patients can identify PPGL before pregnancy.

Indexed as

Adrenal Gland NeoplasmsParagangliomaPheochromocytomaFemaleHumansPregnancyAlpha-adrenergic blockadeBeta-adrenergic blockadeParagangliomaPheochromocytomaPregnancy

Identifiers

PMID33961120
PMCPMC8251512

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.