SynthesisJournal of rehabilitation medicine2021
Increasing prevalence of cerebral palsy among children and adolescents in China 1988-2020: A systematic review and meta-analysis.
Synthesis in Journal of rehabilitation medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 5 of them syntheses that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
24 citing papers in PubMed, 5 syntheses or guidelines pooled it, 34 citations in OpenAlex.
- Born at higher risk: persistent male excess risk of cerebral palsy from extreme prematurity to term: a systematic review and meta-analysis.Biology of sex differences · 2026Pooled it
- Motor imagery ability in children and adolescents with cerebral palsy: a systematic review and evidence map.Frontiers in neurology · 2024Pooled it
- Global prevalence of cerebral palsy: A systematic analysis.Developmental medicine and child neurology · 2022Pooled it
- Efficacy and safety of stem cell therapy in cerebral palsy: A systematic review and meta-analysis.Frontiers in bioengineering and biotechnology · 2022Pooled it
- Effect of Virtual Reality on Balance Function in Children With Cerebral Palsy: A Systematic Review and Meta-analysis.Frontiers in public health · 2022Pooled it
- Identifying SHROOM4 as a novel X-linked susceptibility gene for cerebral palsy in Chinese males.BMC pediatrics · 2026Article
- Trends in the annual incidence and risk factors of cerebral palsy.Pediatric research · 2026Article
- Cerebral cortical activation and functional connectivity characteristics of children with unilateral cerebral palsy during a single-session virtual reality throwing motor task: a functional near-infrared spectroscopy study.Frontiers in rehabilitation sciences · 2026Article
- Article
- Disruptions of morphological brain networks and their associations with multi-symptoms in children with spastic cerebral palsy.Quantitative imaging in medicine and surgery · 2025Article
- Article
- Action Observation for Children and Adolescents with Cerebral Palsy: Hope or Hype? A Systematic Review with Meta-Analysis.Children (Basel, Switzerland) · 2025Review
- Knowledge, attitude and practice of rehabilitation management of the caregivers of pediatric patients with hemiplegia.Scientific reports · 2025Article
- Needs for rehabilitation in China: Estimates based on the Global Burden of Disease Study 1990-2019.Chinese medical journal · 2025Article
- Knowledge mapping of spastic cerebral palsy. A bibliometric analysis of global research (2000-2022).Italian journal of pediatrics · 2024Article
- An analysis of stimulation methods used in rehabilitation equipment for children with cerebral palsy.Frontiers in neurology · 2024Review
- Cerebral Palsy Heterogeneity: Clinical Characteristics and Diagnostic Significance from a Large-Sample Analysis.Neuroepidemiology · 2024Article
- Article
- Multi-Hit White Matter Injury-Induced Cerebral Palsy Model Established by Perinatal Lipopolysaccharide Injection.Frontiers in pediatrics · 2022Article
- The Cost of Neurodevelopmental Disability: Scoping Review of Economic Evaluation Methods.ClinicoEconomics and outcomes research : CEOR · 2022Article
Corrections and comments
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesTo investigate the pooled prevalence of cerebral palsy in China, analyse the differences between different subgroups, and explore the trend over the 32-year period from 1988 to 2020.
methodsAll potential studies related to the prevalence of cerebral palsy among children and adolescents in China were identified from 3 English-language databases and 4 Chinese-language databases. Pooled prevalence was calculated to estimate the prevalence of cerebral palsy among 0-18 years old and different geographical regions in China, using a random-effects meta-analysis model. Continuous fractional polynomial regression modelling was used to estimate the trend in prevalence of cerebral palsy over time. Subgroup analysis and meta-regression were conducted to investigate heterogeneity. Funnel plots and Egger's test were used to explore potential publication bias.
resultsThe pooled prevalence of cerebral palsy over the study period among 0-18 years old and different geographical regions in China was 2.07‰ (95% confidence interval (95% CI) 1.66-2.47‰), and the prevalence of cerebral palsy was higher in males compared with females (2.25‰ vs 1.59‰), and in rural residents compared with urban residents (2.75‰ vs 1.90‰), respectively. The prevalence of cerebral palsy varied significantly between different geographical regions. In subjects with birthweights < 2.5 and > 4 kg, the prevalence of cerebral palsy was significantly higher than in subjects with birthweights between 2.5 and 4 kg. The trend in pooled prevalence of cerebral palsy increased continuously over the period studied, and could be divided into 3 stages; the mean annual increase in prevalence from 1988 to 1996 and from 2008 to 2019 was more rapid. Multivariate meta-regression found that the year of study was one of the sources of heterogeneity among overall prevalence. (p-value = 0.006).
conclusionThe pooled prevalence of cerebral palsy over the 32-year period from 1988 to 2020 was 2.07‰. There was an increasing trend in prevalence of cerebral palsy among children and adolescents in China over this period.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.