Evidence map›Paper›PMID 33960843›Full record

Trial reportAIDS patient care and STDs2021

Correlates of High HIV Viral Load and Antiretroviral Therapy Adherence Among Viremic Youth in the United States Enrolled in an Adherence Improvement Intervention.

K Rivet Amico, Jessica Crawford, Ini Ubong, Jane C Lindsey, Aditya H Gaur, Keith Horvath, Rachel Goolsby, Megan Mueller Johnson, Ronald Dallas, Barbara Heckman and 4 more

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in AIDS patient care and STDs, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03292432 (Triggered Escalating Real-time Adherence Intervention to Promote Rapid HIV Viral Suppression Among Youth Living With HIV Failing Antiretroviral Therapy), which is not on this map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03292432 nacompletednot on this map

Triggered Escalating Real-time Adherence Intervention to Promote Rapid HIV Viral Suppression Among Youth Living With HIV Failing Antiretroviral Therapy: The TERA Study

TypeinterventionalSponsorUniversity of North Carolina, Chapel HillRan2018 to 2020Enrolled89ConditionsHIV InfectionsArmsTERA Intervention (TERA), Standard of Care (SOC)
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 1 country.

K Rivet AmicoDepartment of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.ORCID 0000-0002-4458-6934
Jessica CrawfordDepartment of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Ini UbongDepartment of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Jane C LindseyCenter for Biostatistics in AIDS Research, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
Aditya H GaurDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Keith HorvathDepartment of Clinical Psychology, San Diego State University, San Diego, California, USA.
Rachel GoolsbyDepartment of Biostatistics, Gillings School of Public Health, Collaborative Studies Coordinating Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Megan Mueller JohnsonDepartment of Health Behavior and Health Education, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Ronald DallasDepartment of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, Tennessee, USA.
Barbara HeckmanFrontier Science and Technology Research Foundation, Amherst, New York, USA.
Teresa FilipowiczDepartment of Biostatistics, Gillings School of Public Health, Collaborative Studies Coordinating Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Melissa PolierDepartment of Biostatistics, Gillings School of Public Health, Collaborative Studies Coordinating Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Betty M RuppDepartment of Biostatistics, Gillings School of Public Health, Collaborative Studies Coordinating Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
Michael HudgensDepartment of Biostatistics, Gillings School of Public Health, Collaborative Studies Coordinating Center, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, USA.
University of North Carolina at Chapel Hill · USMichigan Department of Health and Human Services · USSt. Jude Children's Research Hospital · USCancer Research And Biostatistics · USFrontier Science & Technology Research Foundation · USSan Diego State University · US

Funding

Project-003U24HD089880 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI HUDGENS, MICHAEL G, LAVANGE, LISA · 2016 to 2021
$44.3M
NICHD NIH HHS U24 HD089880
6 · The paper itself

Abstract

A sizable portion of youth (ages 13-24) living with HIV in the United States have unsuppressed viral load. The AIDS Interventions (ATN) 152 study [evaluating the Triggered Escalating Real-Time Adherence (TERA) intervention] baseline data were examined to identify correlates of high viremia (>5000 copies/mL) and self-reported adherence, which can help in planning of differentiated services for viremic youth. Depression, HIV-stigma, and cannabis use were common in this sample of 87 youth. Almost half (48%) had high viremia, which associated with enacted stigma, moderate- to high-risk alcohol use, mental health diagnosis, and age ≥21. Self-reported adherence was related to viral load and associated with mental and physical health functioning, depression, social support, self-confident decision-making, total and internalized stigma, adherence motivation, and report of a missed a care visit in the past 6 months. Mental health emerged as a common correlate of viral load and adherence. Clinical Trial Registration number: NCT03292432.

Indexed as

Anti-HIV AgentsHIV InfectionsAdolescentAdultHumansMedication AdherenceUnited StatesViral LoadViremiaYoung AdultAnti-HIV AgentsadherencecorrelatesHIVviral loadyouth

Identifiers

PMID33960843
PMCPMC8106249
OpenAlexW3159710449

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.