ArticleActa ophthalmologica2022
Development of angle closure and associated risk factors: The Handan eye study.
Article in Acta ophthalmologica, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 20 citations in OpenAlex.
- Role of Static and Dynamic Ocular Biometrics Measured in the Dark and Light as Risk Factors for Angle Closure Progression.American journal of ophthalmology · 2023Trial
- Investigation of laser peripheral iridotomy characteristics using the ImageJ program on anterior segment parameters.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Bilateral simultaneous acute angle closure glaucoma triggered by an over-the-counter cold and influenza medication.BMJ case reports · 2024Article
- Characteristics of beta parapapillary atrophy in primary angle-closure suspect.BMJ open ophthalmology · 2024Observational
- Oxidative Stress: A Suitable Therapeutic Target for Optic Nerve Diseases?Antioxidants (Basel, Switzerland) · 2023Review
- Structural measurements and vessel density of spectral-domain optic coherence tomography in early, moderate, and severe primary angle-closure glaucoma.International journal of ophthalmology · 2023Article
- Detecting eyes with high risk of angle closure among apparently normal eyes by anterior segment OCT: a health examination center-based model.BMC ophthalmology · 2022Article
- Ultrasound biomicroscopic imaging demonstrate thinner ciliary body thickness in eyes with angle closure.International journal of ophthalmology · 2022Article
- Smartphone-Acquired Anterior Segment Images for Deep Learning Prediction of Anterior Chamber Depth: A Proof-of-Concept Study.Frontiers in medicine · 2022Article
- Distribution of White-to-White Corneal Diameter and Anterior Chamber Depth in Chinese Myopic Patients.Frontiers in medicine · 2021Article
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Authors and funding
5 authors at 4 institutions in 2 countries.
Funding
Abstract
purposeTo investigate the development of angle closure from baseline open angle and associated risk factors in a rural Chinese population through a longitudinal study over a 5-year period.
methodsSubjects aged ≥30 years and older with bilateral open angles at baseline of the Handan Eye Study who participated in the follow-up and had undergone both baseline and follow-up gonioscopic examinations were included. Subjects with any form of angle closure, glaucoma, incisional ocular surgery or other conditions that could influence the results were excluded. The development of angle closure was defined as the presence of primary angle closure suspect (PACS) or primary angle closure (PAC)/primary angle closure glaucoma (PACG) during the follow-up in normal subjects with baseline bilateral open angles. Logistic regression was performed to identify the baseline risk factors for the development of angle closure.
resultsA total of 457 subjects with bilateral open angles at baseline aged 53.0 (45.5, 58.0) years were enrolled. 94.7% of the included cases developed PACS, 5.3% developed PAC and no one developed PACG after 5 years. In logistic regression, significant risk factors for the development of angle closure were shallower central anterior chamber depth (ACD) (p = 0.002) and narrower mean angle width (p < 0.001).
conclusionsThis study reports the development from baseline open angle to angle closure after a 5-year follow-up. We confirm that the mean angle width and central ACD were independent predictive risk factors for the development of any form of angle closure.
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