ArticleJournal of clinical hypertension (Greenwich, Conn.)2021
Age-related alterations in cardiac and arterial structure and function in hypertensive women and men.
Article in Journal of clinical hypertension (Greenwich, Conn.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 18 citations in OpenAlex.
- Analysis of the association between history of gestational diabetes mellitus and hypertensive disorders in a subsequent pregnancy: a retrospective cohort study.Frontiers in endocrinology · 2026Article
- Local large arterial perivascular adipose tissue metabolic and anatomical features are associated with hypertensive clinical outcomes: a PET/CT-based study.Annals of medicine · 2025Article
- Influence of Echocardiographic Criteria on the Prevalence and Prognostic Implication of Left Ventricular Hypertrophy: A Nationwide Population-Based Study.Journal of the American Heart Association · 2025Article
- Metabolic syndrome, left ventricular diastolic dysfunction and heart failure with preserved ejective fraction.Frontiers in endocrinology · 2025Review
- Positive additive interaction effects of age, sex, obesity, and metabolic syndrome on left ventricular dysfunction.Journal of diabetes · 2024Article
- The Safety and Antiaging Effects of Nicotinamide Mononucleotide in Human Clinical Trials: an Update.Advances in nutrition (Bethesda, Md.) · 2023Review
- Prognostic implications of left ventricular hypertrophy defined by the thresholds from the international and Chinese guidelines.Journal of clinical hypertension (Greenwich, Conn.) · 2023Article
- Longitudinal Study of Left Ventricular Mass Index Trajectories and Risk of Mortality in Hypertension: A Cohort Study.Journal of the American Heart Association · 2023Article
- Prevalence and prognosis of left ventricular diastolic dysfunction in community hypertension patients.BMC cardiovascular disorders · 2022Article
- Association of Office and Ambulatory Blood Pressure with Left Ventricular Structure and Function in Hypertensive Patients.International journal of general medicine · 2022Article
- Age-related alterations in cardiac and arterial structure and function in hypertensive women and men.Journal of clinical hypertension (Greenwich, Conn.) · 2021Article
- Sex-Specific Age-Related Changes in Methylation of Certain Genes.Sovremennye tekhnologii v meditsine · 2021Article
Corrections and comments
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study was to compare age-related alterations in cardiac and arterial structure and function by sex and to explore the impacts of achieved systolic blood pressure (SBP; <130 mm Hg vs. <140 mm Hg) level on age-related alterations in cardiac and arterial structure and function in hypertensive women and men. Community hypertensive individuals without cardiovascular disease who had echocardiographic examination were included. Age-related alterations in cardiac and arterial structure and function were compared by sex, and interplay between age and sex was analyzed according to achieved SBP level. The mean age of the cohort was 66.5 years, and women accounted for 62% (n = 602) of the cohort (n = 971). Compared to men, women had worse left ventricular (LV) diastolic function and greater LV and arterial stiffness. After adjusting for covariates, the magnitude of the associations between age with septal E/e' ratio, septal S' velocity, effective arterial elastance (Ea) and LV end-diastolic elastance (Eed) were greater in women. Sex differences in the magnitude of association between age with these four indices varied according to achieved SBP level. When achieved SBP <130 mm Hg, the magnitude of the associations between age with septal E/e' ratio, septal S' velocity, Ea and Eed did not differ by sex. Since age and sex are non-modifiable, achieving SBP target, especially at a lower level, might be beneficial to attenuate sex differences in age-related alterations in cardiac and arterial structure and function.
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