Evidence map›Paper›PMID 33960110›Full record

SynthesisObesity reviews : an official journal of the International Association for the Study of Obesity2021

Effect of exercise on cardiometabolic health of adults with overweight or obesity: Focus on blood pressure, insulin resistance, and intrahepatic fat-A systematic review and meta-analysis.

Francesca Battista, Andrea Ermolao, Marleen A van Baak, Kristine Beaulieu, John E Blundell, Luca Busetto, Eliana V Carraça, Jorge Encantado, Dror Dicker, Nathalie Farpour-Lambert and 3 more

2 registry-linked trialsOpen access · hybridAbstract readMeta-AnalysisSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Obesity reviews : an official journal of the International Association for the Study of Obesity, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 83 papers, 10 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
83citing papers in PubMed, 10 pooled it
11.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06518486 nacompletednot on this mapstarted 2024, after this paper: background citation

The Effectiveness of Foot-Ankle Exercise and Walking Exercise on Foot Neuropathy, Stress, Quality of Life, Blood Sugar Markers, Blood Pressure, Ankle-Brachial Index, and BMI Among Diabetes Mellitus Patients

TypeinterventionalSponsorTaipei Medical UniversityRan2024 to 2025Enrolled375ConditionsDiabetic Foot, Diabetes Mellitus, Type 2, Diabetic Neuropathies, Diabetes Type 2ArmsFoot-ankle exercise, Walking exercise, Usual care and health education
NCT07270328 nacompletednot on this mapstarted 2024, after this paper: background citation

A Pilot Study of Feasibility and Exploratory Study for a Definitive Randomised Controlled Trial of Foot-Ankle Versus Walking Exercises in Patients With Diabetes Mellitus: Effects on Neuropathy, Stress, and Quality of Life

TypeinterventionalSponsorTaipei Medical UniversityRan2024 to 2024Enrolled108ConditionsDiabete Mellitus, Diabete Type 2, Diabetic Peripheral Neuropathy, Diabetic FootArmsFoot-ankle exercise group, Walking exercise group, Control group
3 · Its place in the literature

Who cites it

83 citing papers in PubMed, 10 syntheses or guidelines pooled it, 121 citations in OpenAlex.

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  13. Brain patterns and risk factors in the FINGER RCT multimodal lifestyle intervention.The journal of prevention of Alzheimer's disease · 2025
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  19. Beyond weight loss: the value of physical activity and exercise for improving cardiometabolic risk factors in individuals with overweight and obesity.Netherlands heart journal : monthly journal of the Netherlands Society of Cardiology and the Netherlands Heart Foundation · 2026
    Review
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23 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 8 countries.

Francesca BattistaSport and Exercise Medicine Division, Department of Medicine, University of Padova, Padua, Italy.ORCID 0000-0003-0760-1354
Andrea ErmolaoSport and Exercise Medicine Division, Department of Medicine, University of Padova, Padua, Italy.ORCID 0000-0002-0546-1514
Marleen A van BaakNUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-2592-6363
Kristine BeaulieuAppetite Control and Energy Balance Research Group (ACEB), School of Psychology, Faculty of Medicine and Health, University of Leeds, Leeds, UK.ORCID 0000-0001-8926-6953
John E BlundellAppetite Control and Energy Balance Research Group (ACEB), School of Psychology, Faculty of Medicine and Health, University of Leeds, Leeds, UK.ORCID 0000-0002-7085-9596
Luca BusettoObesity Management Task Force (OMTF), European Association for the Study of obesity (EASO).ORCID 0000-0003-4883-8980
Eliana V CarraçaFaculdade de Educação Física e Desporto, CIDEFES, Universidade Lusófona de Humanidades e Tecnologias, Lisbon, Portugal.ORCID 0000-0002-5789-811X
Jorge EncantadoAPPsyCI - Applied Psychology Research Center Capabilities & Inclusion, ISPA - University Institute, Lisbon, Portugal.ORCID 0000-0003-0542-8340
Dror DickerObesity Management Task Force (OMTF), European Association for the Study of obesity (EASO).ORCID 0000-0001-8546-6245
Nathalie Farpour-LambertObesity Management Task Force (OMTF), European Association for the Study of obesity (EASO).ORCID 0000-0001-6478-7269
Adriyan PramonoNUTRIM School of Nutrition and Translational Research in Metabolism, Department of Human Biology, Maastricht University, Maastricht, The Netherlands.ORCID 0000-0003-2159-4576
Alice BellichaINSERM, Nutrition and Obesities: Systemic Approaches (NutriOmics), Sorbonne University, Paris, France.ORCID 0000-0002-5572-487X
Jean-Michel OppertAssistance Publique-Hôpitaux de Paris (AP-HP), Pitié-Salpêtrière hospital, Department of Nutrition, Institute of Cardiometabolism and Nutrition, Sorbonne University, Paris, France.ORCID 0000-0003-0324-4820
University of Padua · ITMaastricht University · NLUniversity of Leeds · GBInserm · FRSorbonne Université · FRTel Aviv University · ILUniversidade Lusófona · PTUniversity of Geneva · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This systematic review examined the impact of exercise intervention programs on selected cardiometabolic health indicators in adults with overweight or obesity. Three electronic databases were explored for randomized controlled trials (RCTs) that included adults with overweight or obesity and provided exercise-training interventions. Effects on blood pressure, insulin resistance (homeostasis model of insulin resistance, HOMA-IR), and magnetic resonance measures of intrahepatic fat in exercise versus control groups were analyzed using random effects meta-analyses. Fifty-four articles matched inclusion criteria. Exercise training reduced systolic and diastolic blood pressure (mean difference, MD = -2.95 mmHg [95% CI -4.22, -1.68], p < 0.00001, I

Indexed as

Cardiovascular DiseasesInsulin ResistanceAdultBlood PressureExerciseHumansObesityOverweighthypertensioninsulin resistancemorbid obesityNAFLDphysical activitytype 2 diabetes

Identifiers

PMID33960110
PMCPMC8365642
OpenAlexW3159182860

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.