ArticleAdvanced materials (Deerfield Beach, Fla.)2021
A Floating Mold Technique for the Programmed Assembly of Protocells into Protocellular Materials Capable of Non-Equilibrium Biochemical Sensing.
Article in Advanced materials (Deerfield Beach, Fla.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
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The trial behind it
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Who cites it
13 citing papers in PubMed.
- Prototissues: Assembly strategies, collective behaviors, and emerging applications.Bioactive materials · 2026Review
- One-step construction of robust protocells and prototissues in water.Nature communications · 2026Article
- A Photonastic Prototissue Capable of Photo-Mechano-Chemical Transduction.Advanced materials (Deerfield Beach, Fla.) · 2025Article
- Continuous Light-Induced Water Oxidation in Polyoxometalate-Based Photocatalytic Protocells and Prototissues.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Article
- Programmed Fabrication of Vesicle-Based Prototissue Fibers with Modular Functionalities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Organelle-like structural evolution of coacervate droplets induced by photopolymerization.Nature communications · 2025Article
- A Photo-degradable Crosslinker for the Development of Light-responsive Protocell Membranes.Chemistry (Weinheim an der Bergstrasse, Germany) · 2023Article
- Engineering Tissue-Scale Properties with Synthetic Cells: Forging One from Many.ACS synthetic biology · 2023Review
- Signal processing and generation of bioactive nitric oxide in a model prototissue.Nature communications · 2022Article
- High-throughput production of functional prototissues capable of producing NO for vasodilation.Nature communications · 2022Article
- Chemical Communication in Artificial Cells: Basic Concepts, Design and Challenges.Frontiers in molecular biosciences · 2022Review
- A Floating Mold Technique for the Programmed Assembly of Protocells into Protocellular Materials Capable of Non-Equilibrium Biochemical Sensing.Advanced materials (Deerfield Beach, Fla.) · 2021Article
- Bioinspired Networks of Communicating Synthetic Protocells.Frontiers in molecular biosciences · 2021Review
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Despite important breakthroughs in bottom-up synthetic biology, a major challenge still remains the construction of free-standing, macroscopic, and robust materials from protocell building blocks that are stable in water and capable of emergent behaviors. Herein, a new floating mold technique for the fabrication of millimeter- to centimeter-sized protocellular materials (PCMs) of any shape that overcomes most of the current challenges in prototissue engineering is reported. Significantly, this technique also allows for the generation of 2D periodic arrays of PCMs that display an emergent non-equilibrium spatiotemporal sensing behavior. These arrays are capable of collectively translating the information provided by the external environment and are encoded in the form of propagating reaction-diffusion fronts into a readable dynamic signal output. Overall, the methodology opens up a route to the fabrication of macroscopic and robust tissue-like materials with emergent behaviors, providing a new paradigm of bottom-up synthetic biology and biomimetic materials science.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.