Evidence map›Paper›PMID 33959793›Full record

ArticleOsteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA2021

Preoperative severe vitamin D deficiency is a significant independent risk factor for poorer functional outcome and quality of life 6 months after surgery for fragility hip fractures.

D S Sim, K Tay, T S Howe, S B J Koh

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Article in Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

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11citing papers in PubMed
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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Review
  2. 25-Hydroxyvitamin D Levels, Free Serum Calcium, Glomerular Filtration Rate, Albumin, and Femoral Fracture Elderly Patient Mortality.Journal of the American Academy of Orthopaedic Surgeons. Global research & reviews · 2026
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  3. Review
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  11. A decrease in serum 1,25(OH)Journal of endocrinological investigation · 2022
    Article
4 · The record

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5 · Who and what money

Authors and funding

4 authors.

D S SimDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore. davidsimshaoen@gmail.com.ORCID http://orcid.org/0000-0002-7716-0980
K TayDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.ORCID https://orcid.org/0000-0003-3841-9651
T S HoweDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.ORCID https://orcid.org/0000-0002-2933-6830
S B J KohDepartment of Orthopaedic Surgery, Singapore General Hospital, Singapore, Singapore.ORCID https://orcid.org/0000-0003-4135-0288

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hip fractures are common in the elderly, and many patients with hip fractures have low vitamin D levels. This study found that severe vitamin D deficiency is linked to poorer recovery of function and quality of life after hip fracture surgery.

introductionVitamin D deficiency is prevalent in hip fracture patients and associated with increased mortality and complications. However, there is limited long-term data on how vitamin D levels affect functional outcomes after hip fracture surgery. The aim of this study is to ascertain the association between vitamin D levels and recovery from hip surgery.

methodsPatients who underwent hip fracture surgery from January 2012 to December 2016 and had vitamin D levels assessed during admission were included. Retrospective analysis was performed on patients' demographic data such as age, gender and clinical parameters such as preoperative vitamin D, haemoglobin levels, Charlson Comorbidity Index (CCI), and type and site of surgery. Patients were divided according to four different vitamin D levels-severe vitamin D deficiency (≤10 ng/mL), mild deficiency (10-20 ng/ml), insufficiency (20-30 ng/ml), and normal (>30ng/ml). Functional outcomes were measured by Harris Hip Score (HHS), Parker Mobility Score (PMS), and individual domains of 36-Item Short Form Health Survey (SF36). Univariate and multivariate analyses were conducted to examine the association between vitamin D deficiency and functional outcome scores.

resultsOut of 664 patients identified, 9% had severe vitamin D deficiency and 39% mild deficiency. Patients with severe vitamin D deficiency had significantly poorer baseline and 6-month PMS and SF36 Physical Functioning (PF). In multivariate analysis, severe vitamin D deficiency was associated with lower 6-month PMS and SF36 PF.

conclusionPreoperative severe vitamin D deficiency is an independent risk factor for poorer recovery of function and quality of life after hip fracture surgery.

Indexed as

Hip FracturesVitamin D DeficiencyAgedHumansQuality of LifeRetrospective StudiesRisk FactorsVitamin DVitamin DFunctional outcomeHip fractureVitamin D

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.