Evidence map›Paper›PMID 33959673›Full record

ArticleTobacco regulatory science2020

Comparison of Measurement Methods for Electronic Cigarette Puff Topography.

Nicholas J Felicione, Nareg Karaoghlanian, Alan Shihadeh, Thomas Eissenberg, Melissa D Blank

Abstract read
In one paragraph

Article in Tobacco regulatory science, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Abuse Liability of Electronic Cigarettes in Never-Smoking Electronic Cigarette Users.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2025
    Trial
  2. Trial
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Comparing POD and MOD ENDS Users' Product Characteristics, Use Behaviors, and Nicotine Exposure.Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco · 2023
    Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Nicholas J FelicioneRoswell Park Comprehensive Cancer Center, Department of Health Behavior, Buffalo, NY, United States.
Nareg KaraoghlanianAmerican University of Beirut, Department of Mechanical Engineering, Beirut, Lebanon.
Alan ShihadehAmerican University of Beirut, Department of Mechanical Engineering, Beirut, Lebanon.
Thomas EissenbergVirginia Commonwealth University, Department of Psychology, Center for the Study of Tobacco Products, Richmond, VA, United States.
Melissa D BlankWest Virginia University, Department of Psychology, WV Prevention Research Center, Morgantown, WV, United States.

Funding

Project 4: Using a prospective cohort survey to test population-level predictions generated by Projects 1-3U54DA036105 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI EISSENBERG, THOMAS EVAN · 2018 to 2022
$20.8M
Training and Education Core p270-287P50DA036105 · NIDA · VIRGINIA COMMONWEALTH UNIVERSITY · PI EISSENBERG, THOMAS EVAN · 2013 to 2017
$19.2M
Research Training Program in the Behavioral and Biomedical SciencesT32GM081741 · NIGMS · WEST VIRGINIA UNIVERSITY · PI BERREBI, ALBERT S, SIMPKINS, JAMES W. · 2008 to 2018
$2.1M
NIDA NIH HHS P50 DA036105NIDA NIH HHS U54 DA036105NIGMS NIH HHS T32 GM081741
6 · The paper itself

Abstract

objectivesMeasurement of electronic cigarette (ECIG) puff topography provides an understanding of how product characteristics and user behavior affect nicotine delivery. However, mouthpiece-based topography devices may affect natural puffing behavior. This study was designed to compare ECIG topography measured by mouthpiece-based eTop computerized device and mouthpiece-free video recordings.

methodsECiG-naïve cigarette smokers (N = 18) and ECIG-experienced users (N = 25) puffed on a standardized ECIG via eTop or conventionally; both sessions were videotaped. Following overnight abstinence, participants experienced one directed (10 puffs, 30 sec IPI) and 2

resultsNo statistically significant differences between methods were observed for topography, heart rate, or abstinence-related subjective effects, and both methods were accurate and reliable. Use of a mouthpiece was perceived to alter aspects of ECIG puffing (eg, "reduce enjoyment).

conclusionsThe mouthpiece-based eTop measures ECIG topography precisely as when no mouthpiece is used, and interferes minimally with subjective ECIG experience. Reliable and valid ECIG topography measurement methods are an important regulatory tool, as they can be used to understand the interplay between product design and user behavior to predict toxicant exposure.

Indexed as

cigarette smokingelectronic cigarettemethodspuff topography

Identifiers

PMID33959673
PMCPMC8096180

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.