Evidence map›Paper›PMID 33959636›Full record

ReviewFrontiers in molecular biosciences2021

Impact of Ribosome Activity on SARS-CoV-2 LNP - Based mRNA Vaccines.

Evangelos Tsiambas, Aristeidis Chrysovergis, Vasileios Papanikolaou, Nicholas Mastronikolis, Vasileios Ragos, Anna Batistatou, Dimitrios Peschos, Nikolaos Kavantzas, Andreas C Lazaris, Efthimios Kyrodimos

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Evangelos TsiambasDepartment of Cytology, Molecular Unit, 417 Veterans Army Hospital (NIMTS), Athens, Greece.
Aristeidis Chrysovergis1st ENT Department, Hippocration Hospital, National and Kapodistrian University, Athens, Greece.
Vasileios Papanikolaou1st ENT Department, Hippocration Hospital, National and Kapodistrian University, Athens, Greece.
Nicholas MastronikolisENT Department, Medical School, University of Patras, Patras, Greece.
Vasileios RagosDepartment of Maxillofacial, Medical School, University of Ioannina, Ioannina, Greece.
Anna BatistatouDepartment of Pathology, Medical School, University of Ioannina, Ioannina, Greece.
Dimitrios PeschosDepartment of Physiology, Medical School, University of Ioannina, Ioannina, Greece.
Nikolaos KavantzasDepartment of Pathology, Medical School, National and Kapodistrian University, Athens, Greece.
Andreas C LazarisDepartment of Pathology, Medical School, National and Kapodistrian University, Athens, Greece.
Efthimios Kyrodimos1st ENT Department, Hippocration Hospital, National and Kapodistrian University, Athens, Greece.
University of Ioannina · GRHippocration General Hospital · GRNational and Kapodistrian University of Athens · GRUniversity of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronavirus-related Severe Acute Respiratory Syndrome-2 (SARS-CoV-2) initially was detected in Wuhan, Hubei, China. Since early 2021, World Health Organization (WHO) has declared Coronavirus Disease 2019 (COVID-19) a pandemic due to rapidly transformed to a globally massive catastrophic viral infection. In order to confront this emergency situation, many pharmaceutical companies focused on the design and development of efficient vaccines that are considered necessary for providing a level of normalization in totally affected human social-economical activity worldwide. A variety of vaccine types are under development, validation or even some of them have already completed these stages, initially approved as conditional marketing authorisation by Food and Drug Administration (FDA), European Medicines Agency (EMA), and other national health authorities for commercial purposes (

Indexed as

COVID-19LNPmRNAribosomeSARS-CoV-2vaccine

Identifiers

PMID33959636
PMCPMC8093617
OpenAlexW3156496774

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.