Evidence map›Paper›PMID 33959621›Full record

ReviewFrontiers in medicine2021

The Role of Non-coding RNAs in Diabetic Nephropathy-Related Oxidative Stress.

Xiaoyun He, Gaoyan Kuang, Yi Zuo, Shuangxi Li, Suxian Zhou, Chunlin Ou

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. LncRNA MALAT1 Aggravates Renal Tubular InjuryFrontiers in endocrinology · 2022
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Xiaoyun HeDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Gaoyan KuangDepartment of Orthopedics, The First Affiliated Hospital of Hunan University of Chinese Medicine, Changsha, China.
Yi ZuoDepartment of Endocrinology, Affiliated Hospital of Guilin Medical University, Guilin, China.
Shuangxi LiDepartment of Pathophysiology, Hunan University of Medicine, Huaihua, China.
Suxian ZhouDepartment of Endocrinology, Affiliated Hospital of Guilin Medical University, Guilin, China.
Chunlin OuDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Guilin Medical University · CNXiangya Hospital Central South University · CNFirst Affiliated Hospital of Hunan University of Traditional Chinese Medicine · CNHunan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diabetic nephropathy (DN) is one of the main complications of diabetes and the main cause of diabetic end-stage renal disease, which is often fatal. DN is usually characterized by progressive renal interstitial fibrosis, which is closely related to the excessive accumulation of extracellular matrix and oxidative stress. Non-coding RNAs (ncRNAs) are RNA molecules expressed in eukaryotic cells that are not translated into proteins. They are widely involved in the regulation of biological processes, such as, chromatin remodeling, transcription, post-transcriptional modification, and signal transduction. Recent studies have shown that ncRNAs play an important role in the occurrence and development of DN and participate in the regulation of oxidative stress in DN. This review clarifies the functions and mechanisms of ncRNAs in DN-related oxidative stress, providing valuable insights into the prevention, early diagnosis, and molecular therapeutic targets of DN.

Indexed as

diabetic nephropathymircoRNAncRNAoxidative stresstherapeutic target

Identifiers

PMID33959621
PMCPMC8093385
OpenAlexW3153636330

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.