ReviewFrontiers in bioengineering and biotechnology2021
Extraction, Purification, Bioactivities and Application of Matrix Proteins From Pearl Powder and Nacre Powder: A Review.
Review in Frontiers in bioengineering and biotechnology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 39 citations in OpenAlex.
- Mollusk-Derived Peptides at the Food-Pharma Interface: Bioactivities, Preclinical Evidence, and Development Prospects.Molecules (Basel, Switzerland) · 2026Review
- Natural Nacre-Derived Biomimetic Materials for In Vivo Bone Regeneration.Biomimetics (Basel, Switzerland) · 2026Article
- Effect of the water-soluble matrix of nanometer pearl powder on the osteogenic differentiation of hFOB1.19 cells.Experimental and therapeutic medicine · 2026Article
- Preliminary Preclinical Evaluation of Innovative Bone Scaffolds Composed of Natural Sources-Whey Protein Isolate and Pearl Powder.International journal of molecular sciences · 2025Article
- Margarita (Pearl) Extract Alleviates Melasma by Targeting CAMP-Responsive Element Binding Protein 1.Journal of cosmetic dermatology · 2025Article
- Integrating Data Mining with Metabolomics to Analyze the Mechanism of the "Pearl-Borneol" Pair in Promoting Healing of Diabetic Wounds.Endocrine, metabolic & immune disorders drug targets · 2025Article
- Generation of Pearl/Calcium Phosphate Composite Particles and Their Integration into Porous Chitosan Scaffolds for Bone Regeneration.Journal of functional biomaterials · 2024Article
- The Use of Shells of Marine Molluscs in Spanish Ethnomedicine: A Historical Approach and Present and Future Perspectives.Pharmaceuticals (Basel, Switzerland) · 2023Review
- Nacre Extract from Pearl Oyster Shell Prevents D-Galactose-Induced Brain and Skin Aging.Marine biotechnology (New York, N.Y.) · 2023Article
- Preclinical safety study of nacre powder in an intraosseous sheep model.BMJ open science · 2022Article
- Efficacy of Water-Soluble Pearl Powder Components Extracted by a COMaterials (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Natural pearls are formed when sand or parasites (irritants) accidentally enter into the oyster body and form pearls under the cover of the nacre layer. Pearl powder is a powdery substance by grinding pearls into small grains, however, the nacre powder is the inner layer of outer corner layer and middle prism layer. Pearl medicine in China has a history of more than 2,000 years, pearl has the effects of calming the mind, clearing the eyes, detoxifying the muscle and so on. In this paper, the researches on the extraction of pearl powder and nacre powder, the isolation and purification of matrix protein and the various biological activities (osteogenic activity, antioxidant, anti-inflammatory, anti-apoptotic, promoting the migration of fibroblasts, and so on) are reviewed in detail. To provide readers with a faster understanding, the method of extraction and purification and the application of nacre powder and pearl powder are clearly presented in the form of figures and tables. In line with the concept of waste or by-product, there are more reports of nacre extract than pearl extract, due to the expensive and limited in origin of pearls. Mainly on the direct use of nacre powder and pearl powder or on the use of extracts (mainly water soluble proteins) through experiments
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.