Evidence map›Paper›PMID 33959509›Full record

ArticleFrontiers in oncology2021

Risk Adapted Ablative Radiotherapy After Intensive Chemotherapy for Locally Advanced Pancreatic Cancer.

Gabriella Rossi, Nicola Simoni, Salvatore Paiella, Roberto Rossi, Martina Venezia, Renato Micera, Giuseppe Malleo, Roberto Salvia, Tommaso Giuliani, Anthony Di Gioia and 6 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.7field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Article
  3. Stereotactic Body Radiation Therapy for Locally Advanced Pancreatic Cancer.Clinical and experimental gastroenterology · 2024
    Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 1 institution in 1 country.

Gabriella RossiDepartment of Radiation Oncology, University of Verona Hospital Trust, Verona, Italy.
Nicola SimoniDepartment of Radiation Oncology, University of Verona Hospital Trust, Verona, Italy.
Salvatore PaiellaDepartment of General and Pancreatic Surgery, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Roberto RossiDepartment of Radiation Oncology, University of Verona Hospital Trust, Verona, Italy.
Martina VeneziaDepartment of Radiation Oncology, University of Verona Hospital Trust, Verona, Italy.
Renato MiceraDepartment of Radiation Oncology, University of Verona Hospital Trust, Verona, Italy.
Giuseppe MalleoDepartment of General and Pancreatic Surgery, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Roberto SalviaDepartment of General and Pancreatic Surgery, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Tommaso GiulianiDepartment of General and Pancreatic Surgery, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Anthony Di GioiaDepartment of General and Pancreatic Surgery, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Alessandra AuriemmaDepartment of Oncology, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Michele MilellaDepartment of Oncology, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Stefania GuarigliaDepartment of Medical Physics, University of Verona Hospital Trust, Verona, Italy.
Carlo CavedonDepartment of Medical Physics, University of Verona Hospital Trust, Verona, Italy.
Claudio BassiDepartment of General and Pancreatic Surgery, Pancreas Institute, University of Verona Hospital Trust, Verona, Italy.
Renzo MazzarottoDepartment of Radiation Oncology, University of Verona Hospital Trust, Verona, Italy.
University of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectiveTo assess the efficacy of a Risk-Adapted Ablative Radiotherapy (RAdAR) approach, after intensive induction chemotherapy, in patients with locally advanced pancreatic cancer (LAPC). MATERIAL AND

methodsPatients with LAPC who received RAdAR following induction chemotherapy from January 2017 to December 2019 were included in this observational study. The RAdAR approach consisted of an anatomy- and simultaneous integrated boost (SIB)-based dose prescription strategy. RAdAR was delivered with stereotactic ablative radiation therapy (SAbR), administering 30 Gy in 5 fractions to the tumor volume (PTV

resultsSixty-four LAPC patients were included.

conclusionsThe RAdAR approach, following intensive induction chemotherapy, is an effective radiation treatment strategy for selected LAPC patients, representing a promising therapeutic option in a multimodality treatment regimen.

Indexed as

ablative dosehypofractionated ablative radiationlocally advancedpancreatic cancerSAbRSBRT (stereotactic body radiation therapy)

Identifiers

PMID33959509
PMCPMC8093383
OpenAlexW3153221205

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.