Evidence map›Paper›PMID 33959473›Full record

ArticleAnalytical cellular pathology (Amsterdam)2021

Ultrasound-Targeted Microbubble Destruction Enhances Inhibitory Effect of Apatinib on Angiogenesis in Triple Negative Breast Carcinoma Xenografts.

Dengke Hong, Jiajia Yang, Jingjing Guo, Yu Zhang, Zhikui Chen

Open access · goldAbstract read
In one paragraph

Article in Analytical cellular pathology (Amsterdam), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Dengke HongDepartment of Vascular Surgery, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Jiajia YangDepartment of Ultrasound, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.ORCID https://orcid.org/0000-0003-3508-4024
Jingjing GuoDepartment of Ultrasound, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Yu ZhangDepartment of Ultrasound, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Zhikui ChenDepartment of Ultrasound, Fujian Medical University Union Hospital, Fuzhou, Fujian, China.
Fujian Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultrasound-targeted microbubble destruction (UTMD) has been proven as an effective technique to assist drugs to cross the vascular wall and cell membrane. This study was aimed at evaluating the synergistic antiangiogenic and growth-inhibiting effects of apatinib (APA) and UTMD on the triple negative breast cancer (TNBC). The TNBC xenograft model was established in nude mice (

Indexed as

MicrobubblesAnimalsAntineoplastic AgentsCell Line, TumorFemaleHumansMiceMice, Inbred BALB CMice, NudeNeovascularization, PathologicPyridinesTriple Negative Breast NeoplasmsTumor BurdenUltrasonic TherapyUltrasonographyVascular Endothelial Growth Factor AAntineoplastic AgentsapatinibPyridinesVascular Endothelial Growth Factor A

Identifiers

PMID33959473
PMCPMC8075700
OpenAlexW3155570692

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.