Evidence map›Paper›PMID 33959148›Full record

ArticleFrontiers in genetics2021

Luminal A Breast Cancer Co-expression Network: Structural and Functional Alterations.

Diana García-Cortés, Enrique Hernández-Lemus, Jesús Espinal-Enríquez

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 23 citations in OpenAlex.

  1. Canonical Pathways Rewiring in Alzheimer's Disease.International journal of molecular sciences · 2026
    Article
  2. Loss of long-range co-expression is a common feature in cancer.NPJ systems biology and applications · 2026
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  19. Modularity in Biological Networks.Frontiers in genetics · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Diana García-CortésComputational Genomics Division, National Institute of Genomic Medicine, Mexico City, Mexico.
Enrique Hernández-LemusComputational Genomics Division, National Institute of Genomic Medicine, Mexico City, Mexico.
Jesús Espinal-EnríquezComputational Genomics Division, National Institute of Genomic Medicine, Mexico City, Mexico.
Universidad Nacional Autónoma de México · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Luminal A is the most common breast cancer molecular subtype in women worldwide. These tumors have characteristic yet heterogeneous alterations at the genomic and transcriptomic level. Gene co-expression networks (GCNs) have contributed to better characterize the cancerous phenotype. We have previously shown an imbalance in the proportion of intra-chromosomal (

Indexed as

breast cancerCTCF binding site analysisgene co-expression networksloss of long range co-expressionLuminal A breast cancertranscription factor analysis

Identifiers

PMID33959148
PMCPMC8096206
OpenAlexW3155555226

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.