Evidence map›Paper›PMID 33959129›Full record

ArticleFrontiers in immunology2021

Released Myeloperoxidase Attenuates Neutrophil Migration and Accumulation in Inflamed Tissue.

Jacob F Rehring, Triet M Bui, Carlos Samuel Galán-Enríquez, Jessica M Urbanczyk, Xingsheng Ren, Hannah L Wiesolek, David P Sullivan, Ronen Sumagin

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
1.9field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 34 citations in OpenAlex.

  1. Alveolar macrophage-neutrophil crosstalk in acute lung injury: mechanisms, feedback loops, and therapeutic opportunities.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
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  11. Current issues in molecular biology · 2024
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  13. SelectedMolecules (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jacob F RehringDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Triet M BuiDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Carlos Samuel Galán-EnríquezDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Jessica M UrbanczykDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Xingsheng RenDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Hannah L WiesolekDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
David P SullivanDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Ronen SumaginDepartment of Pathology, Northwestern University Feinberg School of Medicine, Chicago, IL, United States.
Northwestern University · US

Funding

Neutrophils instruct macrophage responses to promote mucosal healingR01DK124199 · NIDDK · NORTHWESTERN UNIVERSITY AT CHICAGO · PI SUMAGIN, RONEN · 2020 to 2023
$1.4M
NIDDK NIH HHS R01 DK124199
6 · The paper itself

Abstract

Neutrophil (PMN) recruitment to sites of insult is critical for host defense, however excessive PMN activity and tissue accumulation can lead to exacerbated inflammation and injury. Myeloperoxidase (MPO) is a PMN azurophilic granule enzyme, which together with H

Indexed as

AnimalsChemotaxis, LeukocyteDisease Models, AnimalEndothelial CellsGene ExpressionInflammationMiceMice, KnockoutNeutrophil InfiltrationNeutrophilsPeroxidasePeroxidaseadhesionimaginginflammationmigrationmyeloperoxidase (MPO)neutrophils

Identifiers

PMID33959129
PMCPMC8093447
OpenAlexW3155881911

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.