Evidence map›Paper›PMID 33959127›Full record

ArticleFrontiers in immunology2021

Vaccine Inoculation Route Modulates Early Immunity and Consequently Antigen-Specific Immune Response.

Pierre Rosenbaum, Nicolas Tchitchek, Candie Joly, André Rodriguez Pozo, Lev Stimmer, Sébastien Langlois, Hakim Hocini, Leslie Gosse, David Pejoski, Antonio Cosma and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed
4.7field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 78 citations in OpenAlex.

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  9. mRNA-LNP vaccine encoding theMolecular therapy. Nucleic acids · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 7 institutions in 1 country.

Pierre RosenbaumUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
Nicolas TchitchekUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
Candie JolyUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
André Rodriguez PozoUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
Lev StimmerINSERM, U1169, Kremlin-Bicêtre, France.
Sébastien LangloisUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
Hakim HociniVaccine Research Institute, Henri Mondor Hospital, Créteil, France.
Leslie GosseUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
David PejoskiUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
Antonio CosmaUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
Anne-Sophie BeignonUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
Nathalie Dereuddre-BosquetUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
Yves LevyVaccine Research Institute, Henri Mondor Hospital, Créteil, France.
Roger Le GrandUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
Frédéric MartinonUMR1184 IMVA-HB, IDMIT Department, Université Paris-Saclay - INSERM U1184 - CEA, Fontenay-aux-Roses, France.
CEA Paris-Saclay · FRCommissariat à l'Énergie Atomique et aux Énergies Alternatives · FRInstitut de Recherche Vaccinale · FRUniversité Paris-Saclay · FRCEA Paris-Saclay - Etablissement de Fontenay-aux-roses · FRInserm · FRParis-Est Sup · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination is one of the most efficient public healthcare measures to fight infectious diseases. Nevertheless, the immune mechanisms induced

Indexed as

VaccinationAnimalsAntibodies, NeutralizingAntibodies, ViralCD8-Positive T-LymphocytesInjections, IntradermalInjections, IntramuscularMacaca fascicularisMaleMyeloid-Derived Suppressor CellsVaccines, AttenuatedVacciniaVaccinia virusViral VaccinesAntibodies, NeutralizingAntibodies, ViralVaccines, AttenuatedViral Vaccinesadministration routesinnate & adaptive immune responsemass cytometry (CyTOF)modified vaccinia Ankara (MVA)non human primatesvaccine

Identifiers

PMID33959127
PMCPMC8093451
OpenAlexW3152567964

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.