Evidence map›Paper›PMID 33958791›Full record

ArticleNature chemical biology2021

Architecture of the membrane-bound cytochrome c heme lyase CcmF.

Anton Brausemann, Lin Zhang, Lorena Ilcu, Oliver Einsle

Open access · greenAbstract read
In one paragraph

Article in Nature chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

  1. Heme handling in the system II heme lyase CcsBA from Bacteroides thetaiotaomicron.Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry · 2026
    Article
  2. Article
  3. Article
  4. Mitochondrial genome ofFrontiers in plant science · 2026
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Handling heme with care.Nature chemical biology · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Anton BrausemannInstitut für Biochemie, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0001-9135-301X
Lin ZhangInstitut für Biochemie, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.ORCID http://orcid.org/0000-0001-5431-5006
Lorena IlcuInstitut für Biochemie, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany.
Oliver EinsleInstitut für Biochemie, Albert-Ludwigs-Universität Freiburg, Freiburg, Germany. einsle@biochemie.uni-freiburg.de.ORCID http://orcid.org/0000-0001-8722-2893
University of Freiburg · DE

Funding

European Research Council 310656
6 · The paper itself

Abstract

The covalent attachment of one or multiple heme cofactors to cytochrome c protein chains enables cytochrome c proteins to be used in electron transfer and redox catalysis in extracytoplasmic environments. A dedicated heme maturation machinery, whose core component is a heme lyase, scans nascent peptides after Sec-dependent translocation for CX

Indexed as

Cell MembraneLyasesThermus thermophiluscytochrome C synthetaseLyases

Identifiers

PMID33958791
PMCPMC7611092
OpenAlexW3159136559

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.