ArticleScientific reports2021
Variations of risk factors for ischemic stroke and its subtypes in Chinese patients in Taiwan.
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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14 citing papers in PubMed, 23 citations in OpenAlex.
- Global trend and disparity in the burden of ischemic stroke attributable to high body-mass index from 1990 to 2021 and projection to 2050: a systematic analysis based on the Global Burden of Disease Study 2021.Dialogues in health · 2026Article
- Clinical guideline-guided prognostic models of functional disability after acute ischemic stroke: a retrospective cohort study.BMC neurology · 2026Article
- Proinflammatory Risk Factors in Patients with Ischemic Stroke: A Systematic Review and Meta-Analysis.Antioxidants (Basel, Switzerland) · 2025Review
- Exploring stroke risk factors in different genders using Bayesian networks: a cross-sectional study involving a population of 134,382.BMC public health · 2025Article
- Direct medical cost of first-ever acute ischemic stroke in malaysia: a retrospective cohort study.Scientific reports · 2025Article
- Comprehensive analysis of bioinformatics identification TST, SQOR and NRDC is mitochondria-related biomarkers of ischemic cerebral apoplexy.Scientific reports · 2025Article
- Prognostic Models of Mortality Following First-Ever Acute Ischemic Stroke: A Population-Based Retrospective Cohort Study.Health science reports · 2025Article
- Stroke Epidemiology in Asia.Cerebrovascular diseases extra · 2025Review
- ABCD2-I Score Predicts Unplanned Emergency Department Revisits within 72 Hours Due to Recurrent Acute Ischemic Stroke.Diagnostics (Basel, Switzerland) · 2024Article
- Association between Brain-Derived Neurotrophic Factor and Lipid Profiles in Acute Ischemic Stroke Patients.International journal of molecular sciences · 2024Article
- Association of metabolites on ischemic stroke subtypes: a 2-sample Mendelian randomization study.Frontiers in neurology · 2024Article
- Stroke in Asia.Cerebrovascular diseases extra · 2024Review
- Article
- The role of the gut microbiome and its metabolites in cerebrovascular diseases.Frontiers in microbiology · 2023Review
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Authors and funding
4 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Chinese have a higher stroke incidence and a different distribution of ischemic stroke (IS) subtypes as compared with Caucasians. Herein we aimed to investigate the prevalence and associations of major risk factors in IS and its subtypes in Chinese patients. From 2006 to 2011, we included 4953 acute IS patients consecutively recruited in National Taiwan University Hospital Stroke Registry (mean age 68 years; male 59%). For each risk factor, we accessed the proportion in all IS patients, and calculated odds ratios for each main IS subtype versus other subtypes. Multiple logistic regression models were used to adjust for confounders, and to examine the associations of risk factors with IS subtypes. Compared with other ischemic subtypes, large artery atherosclerotic and lacunar strokes were associated with hypertension, diabetes, and hyperlipidaemia, while cardioembolic strokes were associated with ischemic heart disease. Furthermore, the associations with hypertension and diabetes became stronger in lacunar strokes after adjusting for confounders, but not in other ischemic subtypes. Here we report the variable effects of risk factors on different IS subtypes in Chinese patients in Taiwan. Our findings could help shed light on different mechanisms of IS subtypes and provide targets to make more effective strategies for IS prevention.
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