Evidence map›Paper›PMID 33958655›Full record

ArticleScientific reports2021

Expression of VEGFA-mRNA in classical and MSX2-mRNA in non-classical monocytes in patients with spondyloarthritis is associated with peripheral arthritis.

Małgorzata Stec, Michał Seweryn, Mariusz Korkosz, Zofia Guła, Rafał Szatanek, Kazimierz Węglarczyk, Magdalena Rutkowska-Zapała, Marzena Lenart, Marcin Czepiel, Jarosław Czyż and 5 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 1 institution in 1 country.

Małgorzata Stec *Department of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265 Str., 30-663, Kraków, Poland.
Michał Seweryn *Center for Medical Genomics OMICRON, Jagiellonian University Medical College, Kopernika 7c Str., 31-034, Kraków, Poland.
Mariusz KorkoszDepartment of Rheumatology and Balneology, Jagiellonian University Medical College, Jakubowskiego 2 Str., Kraków, Poland.
Zofia GułaDepartment of Rheumatology and Balneology, Jagiellonian University Medical College, Jakubowskiego 2 Str., Kraków, Poland.
Rafał SzatanekDepartment of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265 Str., 30-663, Kraków, Poland.
Kazimierz WęglarczykDepartment of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265 Str., 30-663, Kraków, Poland.
Magdalena Rutkowska-ZapałaDepartment of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265 Str., 30-663, Kraków, Poland.
Marzena LenartDepartment of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265 Str., 30-663, Kraków, Poland.
Marcin CzepielDepartment of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265 Str., 30-663, Kraków, Poland.
Jarosław CzyżDepartment of Cell Biology, Faculty of Biochemistry, Biophysics and Biotechnology, Jagiellonian University, Gronostajowa 7 Str., Kraków, Poland.
Jarosław BaranDepartment of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265 Str., 30-663, Kraków, Poland.
Anna GrucaDepartment of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265 Str., 30-663, Kraków, Poland.
Kamila Wojnar-LasońDepartment of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265 Str., 30-663, Kraków, Poland.
Paweł WołkowCenter for Medical Genomics OMICRON, Jagiellonian University Medical College, Kopernika 7c Str., 31-034, Kraków, Poland. pawel.wolkow@uj.edu.pl.
Maciej SiedlarDepartment of Clinical Immunology, Institute of Pediatrics, Jagiellonian University Medical College, Wielicka 265 Str., 30-663, Kraków, Poland. misiedla@cyf-kr.edu.pl.
Jagiellonian University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Spondyloarthritis (SpA) is characterized by chronic inflammation and structural damage involving spine and peripheral joints. Monocytes, as part of innate immune system, following migration into affected tissue, may play a role in the pathogenesis of SpA. Here, potential associations between osteogenesis-linked gene expression profile in particular monocyte subpopulations and clinical signs of SpA were investigated. The 20 patients with axial and 16 with peripheral SpA were enrolled in the study. Monocyte subpopulations (classical-CD14

Indexed as

Gene ExpressionAdultArthritisFemaleHumansLipopolysaccharide ReceptorsMaleMonocytesReceptors, IgGRNA, MessengerSpondylarthritisVascular Endothelial Growth Factor ALipopolysaccharide ReceptorsReceptors, IgGRNA, MessengerVascular Endothelial Growth Factor AVEGFA protein, human

Identifiers

PMID33958655
PMCPMC8102490
OpenAlexW3159187042

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.