Evidence map›Paper›PMID 33957879›Full record

Trial reportBMC geriatrics2021

Tai Chi exercise improves age-associated decline in cerebrovascular function: a cross-sectional study.

Lili Li, Jingjing Wang, Shaoying Guo, Yangqi Xing, Xiongwen Ke, Yinghao Chen, Yuan He, Shun Wang, Jiayu Wang, Xinwu Cui and 2 more

Abstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BMC geriatrics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Lili Li *Central Laboratory, Renmin Hospital of Wuhan University, 430060, Wuhan, China.
Jingjing Wang *School of Physical Education, Wuhan Sports University, 430079, Wuhan, China.
Shaoying GuoSchool of Physical Education, Wuhan Sports University, 430079, Wuhan, China.
Yangqi XingSchool of Physical Education, Wuhan Sports University, 430079, Wuhan, China.
Xiongwen KeSchool of Physical Education, Wuhan Sports University, 430079, Wuhan, China.
Yinghao ChenSchool of Physical Education, Wuhan Sports University, 430079, Wuhan, China.
Yuan HeCentral Laboratory, Renmin Hospital of Wuhan University, 430060, Wuhan, China.
Shun WangDepartment of Cardiology, Renmin Hospital of Wuhan University, 430060, Wuhan, China.
Jiayu WangDepartment of Medical Ultrasound, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, 430030, Wuhan, China.
Xinwu CuiDepartment of Medical Ultrasound, Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology, 430030, Wuhan, China. cuixinwu@live.cn.
Zhihua WangCentral Laboratory, Renmin Hospital of Wuhan University, 430060, Wuhan, China. zhihuawang@whu.edu.cn.
Lixu TangSchool of Physical Education, Wuhan Sports University, 430079, Wuhan, China. tanglixu@126.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTai Chi exercise has been reported to enhance physical and mental health in the older adults; however, the mechanism remains elusive. TRIAL

designWe recruited 289 older adults practicing Tai Chi for over 3 years, together with 277 age-matched older and 102 young adults as controls. 168 Tai Chi practitioners were successfully matched to 168 older controls aged 60-69 based on a propensity score for statistics.

methodsCerebrovascular function was evaluated by measuring the hemodynamics of the carotid artery. Spearman correlation was performed to validate the age-associated physiological parameters.

resultsCerebrovascular function in older adults significantly degenerated compared with the young, and was substantially correlated with age. Compared with the older control group, Tai Chi practitioners showed significant improvements in CVHI (cerebral vascular hemodynamics indices) Score (P = 0.002), mean blood flow velocity (P = 0.014), maximal blood flow velocity (P = 0.04) and minimum blood flow velocity (P < 0.001), whereas the age-related increases in pulse wave velocity (P = 0.022), characteristic impedance (P = 0.021) and peripheral resistance (P = 0.044) were lowered.

conclusionsThese data demonstrate a rejuvenation role of Tai Chi in improving the age-related decline of the cerebrovascular function.

trial registrationChinese Clinical Trial Registry (ChiCTR1900025187).

Indexed as

Tai JiAgedCross-Sectional StudiesExerciseHumansPulse Wave AnalysisAgeingCerebrovascular functionHealthy ageingTai Chi

Identifiers

PMID33957879
PMCPMC8101197

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.