Evidence map›Paper›PMID 33957724›Full record

Trial reportTurkish journal of medical sciences2021

Investigation of the effects of propofol/ketamine versus propofol/fentanyl on nausea- vomiting administered for sedation in children undergoing magnetic resonance imaging: a prospective randomized double-blinded study

Hacı Semih Gürcan, Ayşe Ülgey, Özlem Öz Gergin, Sibel Seçkin Pehlivan, Karamehmet Yıldız

Open access · bronzeAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Turkish journal of medical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Hacı Semih GürcanDepartment of Anesthesiology and Reanimation, Gümüşhacıköy Government Hospital, Amasya, TurkeyORCID 0000-0002-5823-2299
Ayşe ÜlgeyDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Erciyes University, Kayseri, TurkeyORCID 0000-0002-7634-6214
Özlem Öz GerginDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Erciyes University, Kayseri, TurkeyORCID 0000-0002-1720-0194
Sibel Seçkin PehlivanDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Erciyes University, Kayseri, TurkeyORCID 0000-0003-3215-5616
Karamehmet YıldızDepartment of Anesthesiology and Reanimation, Faculty of Medicine, Erciyes University, Kayseri, TurkeyORCID 0000-0001-9344-6949
Erciyes University · TRTürk Anesteziyoloji ve Reanimasyon Derneği · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background/aim: In this study, we aimed to compare the effects of propofol-ketamine and propofol-fentanyl sedations on post- procedure nausea-vomiting in children undergoing magnetic resonance imaging (MRI). Materials and methods: This study included 100 pediatric patients (2–10 years old) who had propofol-ketamine and propofol-fentanyl for sedation to undergo MRI. The patients were divided into two groups, and sedation was performed through propofol-ketamine (Group K; n = 50) or propofol-fentanyl (Group F; n = 50). For sedation induction, intravenous (IV) bolus of 1.2 mg/kg propofol and 1 mg/kg ketamine were administered in Group K, IV bolus of 1.2 mg/kg propofol, and 1 μg/kg fentanyl in Group F. All patients received 0.5 mg/kg IV bolus propofol in additional doses when the Ramsay Sedation Score (RSS) was below 4 for maintenance. Perioperative heart rate, systolic arterial pressure, peripheral oxygen saturation, respiratory rate, and nausea-vomiting scores were recorded for each patient. Results: There was no difference between the groups in terms of nausea incidences at the 1st hour. However, the rate of vomiting was significantly higher in Group K. Conclusion: In our study, we showed that the vomiting rate was higher in the 1st hour in Group K compared to Group F.

Indexed as

Postoperative Nausea and VomitingChildChild, PreschoolDouble-Blind MethodDrug CombinationsFemaleFentanylHumansHypnotics and SedativesKetamineMagnetic Resonance ImagingMaleOxygen SaturationProcedural SedationPropofolProspective StudiesDrug CombinationsFentanylHypnotics and SedativesKetaminePropofolchilddeep sedationfentanylketamineMagnetic resonance imagingpropofol

Identifiers

PMID33957724
PMCPMC8569730
OpenAlexW3158865654

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.