Evidence map›Paper›PMID 33957559›Full record

ArticleMedical image analysis2021

Brain functional connectivity analysis based on multi-graph fusion.

Jiangzhang Gan, Ziwen Peng, Xiaofeng Zhu, Rongyao Hu, Junbo Ma, Guorong Wu

Abstract read
In one paragraph

Article in Medical image analysis, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Functional magnetic resonance imaging, deep learning, and Alzheimer's disease: A systematic review.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2023
    Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jiangzhang GanCenter for Future Media and School of Computer Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, China; School of natural and Computational Science, Massey University Auckland Campus, Auckland 0745, New Zealand.
Ziwen PengCenter for the Study of Applied Psychology, Guangdong Key Laboratory of Mental Health and Cognitive Science and School of Psychology, South China Normal University, Guangzhou 510631, China.
Xiaofeng ZhuCenter for Future Media and School of Computer Science and Technology, University of Electronic Science and Technology of China, Chengdu 611731, China; School of natural and Computational Science, Massey University Auckland Campus, Auckland 0745, New Zealand.
Rongyao HuSchool of natural and Computational Science, Massey University Auckland Campus, Auckland 0745, New Zealand.
Junbo MaDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC 27599, USA.
Guorong WuDepartment of Psychiatry, University of North Carolina, Chapel Hill, NC 27599, USA; Department of Computer Science, University of North Carolina, Chapel Hill, NC 27599, USA.

Funding

Understanding Selectivity Mechanisms of Network Vulnerability and Resilience in Alzheimer's Disease by Establishing a Neurobiological Basis through Network NeuroscienceRF1AG068399 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2020 to 2020
$1.9M
Understanding Selectivity Mechanisms of Network Vulnerability and Resilience in Alzheimer's Disease by Establishing a Neurobiological Basis through Network NeuroscienceR01AG068399 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2024 to 2024
$481k
Longitudinal Analysis for Early Diagnosis of Alzheimer's DiseaseK01AG049089 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2016 to 2019
$478k
Longitudinal Analysis of the Dynamic Network Disruptions in Alzheimer's DiseaseR21AG059065 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI STYNER, MARTIN ANDREAS, WU, GUORONG · 2018 to 2019
$428k
Uncovering the Heterogeneity of Neurodegeneration Trajectories in Alzheimer's Disease Using a Network Guided Reaction-Diffusion ModelR03AG073927 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2021 to 2022
$317k
Continuing Tool Development for Longitudinal Network Analysis: Enriching the Diagnostic Power of Disease-Specific Connectomic Biomarkers by Deep Graph LearningR03AG070701 · NIA · UNIV OF NORTH CAROLINA CHAPEL HILL · PI WU, GUORONG · 2021 to 2022
$303k
NIA NIH HHS K01 AG049089NIA NIH HHS R01 AG068399NIA NIH HHS R03 AG070701NIA NIH HHS R03 AG073927NIA NIH HHS R21 AG059065NIA NIH HHS RF1 AG068399
6 · The paper itself

Abstract

In this paper, we propose a framework for functional connectivity network (FCN) analysis, which conducts the brain disease diagnosis on the resting state functional magnetic resonance imaging (rs-fMRI) data, aiming at reducing the influence of the noise, the inter-subject variability, and the heterogeneity across subjects. To this end, our proposed framework investigates a multi-graph fusion method to explore both the common and the complementary information between two FCNs, i.e., a fully-connected FCN and a 1 nearest neighbor (1NN) FCN, whereas previous methods only focus on conducting FCN analysis from a single FCN. Specifically, our framework first conducts the graph fusion to produce the representation of the rs-fMRI data with high discriminative ability, and then employs the L1SVM to jointly conduct brain region selection and disease diagnosis. We further evaluate the effectiveness of the proposed framework on various data sets of the neuro-diseases, i.e., Fronto-Temporal Dementia (FTD), Obsessive-Compulsive Disorder (OCD), and Alzheimers Disease (AD). The experimental results demonstrate that the proposed framework achieves the best diagnosis performance via selecting reasonable brain regions for the classification tasks, compared to state-of-the-art FCN analysis methods.

Indexed as

Alzheimer DiseaseBrainBrain MappingHumansMagnetic Resonance ImagingBrain functional connectivity network analysisClassificationData fusionFeature selectionfMRI data

Identifiers

PMID33957559
PMCPMC8934107

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.