Evidence map›Paper›PMID 33957241›Full record

ArticleJournal of the American College of Cardiology2021

Transesophageal Echocardiography in Patients Undergoing Coronary Artery Bypass Graft Surgery.

Thomas S Metkus, Dylan Thibault, Michael C Grant, Vinay Badhwar, Jeffrey P Jacobs, Jennifer Lawton, Sean M O'Brien, Vinod Thourani, Zachary K Wegermann, Brittany Zwischenberger and 1 more

Registry-linked trialOpen access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of the American College of Cardiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07286227 (Assessment of Left Ventricular Function Before Decannulation in Cardiopulmonary Bypass Surgeries), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07286227 not yet recruitingnot on this mapstarted 2026, after this paper: background citation

Assessment of Left Ventricular Function Before Decannulation in Cardiopulmonary Bypass Surgeries: Comparison of the Cardiac Surgeon's Visual Estimation and Transesophageal Echocardiography

TypeobservationalSponsorAtaturk UniversityRan2026 to 2026Enrolled70ConditionsCardiopulmonary Bypass Surgery, Left Ventricular DysfunctionArmsIntraoperative Left Ventricular Function Assessment
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 65 citations in OpenAlex.

  1. Guideline
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  11. Hemodynamic Monitoring in Burn Resuscitation: Current Status.Annals of burns and fire disasters · 2025
    Article
  12. Article
  13. Intraoperative Transesophageal Echocardiographic Guidance in Cardiac Surgery.Journal of cardiovascular development and disease · 2025
    Review
  14. 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery.Interdisciplinary cardiovascular and thoracic surgery · 2025
    Article
  15. 2024 EACTS/EACTAIC/EBCP Guidelines on cardiopulmonary bypass in adult cardiac surgery.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2025
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Thomas S MetkusDivision of Cardiology and Cardiac Surgery, Departments of Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA. Electronic address: Tmetkus1@jhmi.edu.
Dylan ThibaultDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, USA.
Michael C GrantDivisions of Cardiac Anesthesia, Surgical Critical Care and Acute Care Surgery, Departments of Anesthesiology and Critical Care Medicine and Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Vinay BadhwarDepartment of Cardiovascular and Thoracic Surgery, West Virginia University, Morgantown, West Virginia, USA.
Jeffrey P JacobsDivision of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Florida, Gainesville, Florida, USA.
Jennifer LawtonDivision of Cardiac Surgery, Department of Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.
Sean M O'BrienDepartment of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, North Carolina, USA.
Vinod ThouraniDepartment of Cardiovascular Surgery, Marcus Heart Valve Center, Piedmont Heart Institute, Atlanta, Georgia, USA.
Zachary K WegermannDuke Clinical Research Institute, and Division of Cardiology, Department of Medicine, Duke University Health System, Durham, North Carolina, USA.
Brittany ZwischenbergerDepartment of Surgery, Duke University Medical Center, Durham, North Carolina, USA.
Robert HigginsDivision of Thoracic and Cardiovascular Surgery, Department of Surgery, University of Florida, Gainesville, Florida, USA.
Johns Hopkins University · USDuke University · USUniversity of Florida · USClinical Research Institute · USDuke Medical Center · USValve (United States) · USWest Virginia University · US

Funding

Institutional Career Development CoreKL2TR003099 · NCATS · JOHNS HOPKINS UNIVERSITY · PI GEBO, KELLY A · 2019 to 2023
$7.9M
AHRQ HHS HHSP233201500020INCATS NIH HHS KL2 TR003099
6 · The paper itself

Abstract

backgroundThe impact of utilization of intraoperative transesophageal echocardiography (TEE) at the time of isolated coronary artery bypass grafting (CABG) on clinical decision making and associated outcomes is not well understood.

objectivesThe purpose of this study was to determine the association of TEE with post-CABG mortality and changes to the operative plan.

methodsA retrospective cohort study of planned isolated CABG patients from the Society of Thoracic Surgeons Adult Cardiac Surgery Database between January 1, 2011, and June 30, 2019, was performed. The exposure variable of interest was use of intraoperative TEE during CABG compared with no TEE. The primary outcome was operative mortality. The association of TEE with unplanned valve surgery was also assessed.

resultsOf 1,255,860 planned isolated CABG procedures across 1218 centers, 676,803 (53.9%) had intraoperative TEE. The percentage of patients receiving intraoperative TEE increased over time from 39.9% in 2011 to 62.1% in 2019 (p trend <0.0001). CABG patients undergoing intraoperative TEE had lower odds of mortality (adjusted odds ratio: 0.95; 95% confidence interval: 0.91 to 0.99; p = 0.025), with heterogeneity across STS risk groups (p interaction = 0.015). TEE was associated with increased odds of unplanned valve procedure in lieu of planned isolated CABG (adjusted odds ratio: 4.98; 95% confidence interval: 3.98 to 6.22; p < 0.0001).

conclusionsIntraoperative TEE usage during planned isolated CABG is associated with lower operative mortality, particularly in higher-risk patients, as well as greater odds of unplanned valve procedure. These findings support usage of TEE to improve outcomes for isolated CABG for high-risk patients.

Indexed as

AgedCoronary Artery BypassEchocardiography, TransesophagealHumansMiddle AgedPostoperative ComplicationsRetrospective StudiesUnited Statescardiac surgerycoronary artery bypass graftingechocardiographytransesophageal echocardiography

Identifiers

PMID33957241
PMCPMC8876254
OpenAlexW3157030424

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.