Evidence map›Paper›PMID 33957126›Full record

ReviewThe Journal of biological chemistry

Seeing the PDB.

Jane S Richardson, David C Richardson, David S Goodsell

Open access · goldAbstract readHistorical ArticleReview
In one paragraph

Review in The Journal of biological chemistry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Review
  2. Elements and roadmap for interactive molecular graphics and modeling "in the Holodeck".Protein science : a publication of the Protein Society · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Design - a new way to look at old molecules.Journal of integrative bioinformatics · 2022
    Article
  9. VInternational journal of molecular sciences · 2022
    Review
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Jane S RichardsonDepartment of Biochemistry, Duke University, Durham, North Carolina, USA. Electronic address: jsr@kinemage.biochem.duke.edu.
David C RichardsonDepartment of Biochemistry, Duke University, Durham, North Carolina, USA.
David S GoodsellDepartment of Integrative and Computational Biology, The Scripps Research Institute, La Jolla, California, USA; Research Collaboratory for Structural Bioinformatics Protein Data Bank, Rutgers, the State University of New Jersey, Piscataway, New Jersey, USA. Electronic address: goodsell@scripps.edu.
Duke University · USRutgers, The State University of New Jersey · US

Funding

PROJECT 5 - DUKE - STRUCTURE VALIDATION AND IMPROVEMENT FOR PROTEINS AND N. ACIDSP01GM063210 · NIGMS · UNIVERSITY OF CALIF-LAWRENC BERKELEY LAB · PI ADAMS, PAUL DAVID · 2001 to 2021
$33.5M
PDB MANAGEMENT BY THE RESEARCH COLLABORATORY FOR STRUCTURAL BIOINFORMATICSR01GM133198 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI BURLEY, STEPHEN K · 2019 to 2023
$19.3M
Modeling and Interacting with the Visible Molecular CellR01GM120604 · NIGMS · SCRIPPS RESEARCH INSTITUTE, THE · PI AUTIN, LUDOVIC · 2016 to 2025
$4.2M
Extending MolProbity Diagnosis & Healing Methods to Empower Better CryoEM & Xray Models at 2.5-4A Resolution, plus Versioned, Redeposited "GEMS" for Important Individual StructuresR35GM131883 · NIGMS · DUKE UNIVERSITY · PI RICHARDSON, DAVID CLAUDE · 2019 to 2022
$1.7M
NIGMS NIH HHS P01 GM063210NIGMS NIH HHS R01 GM120604NIGMS NIH HHS R01 GM133198NIGMS NIH HHS R35 GM131883
6 · The paper itself

Abstract

Ever since the first structures of proteins were determined in the 1960s, structural biologists have required methods to visualize biomolecular structures, both as an essential tool for their research and also to promote 3D comprehension of structural results by a wide audience of researchers, students, and the general public. In this review to celebrate the 50th anniversary of the Protein Data Bank, we present our own experiences in developing and applying methods of visualization and analysis to the ever-expanding archive of protein and nucleic acid structures in the worldwide Protein Data Bank. Across that timespan, Jane and David Richardson have concentrated on the organization inside and between the macromolecules, with ribbons to show the overall backbone "fold" and contact dots to show how the all-atom details fit together locally. David Goodsell has explored surface-based representations to present and explore biological subjects that range from molecules to cells. This review concludes with some ideas about the current challenges being addressed by the field of biomolecular visualization.

Indexed as

Models, MolecularDatabases, ProteinHistory, 20th CenturyHistory, 21st CenturyHumansMolecular Biologyall-atom contactsmolecular graphicsprotein foldingprotein structureribbon drawingsRNA structurescience education and outreachstructural biologyvisualizationX-ray crystallography

Identifiers

PMID33957126
PMCPMC8167287
OpenAlexW3157305909

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.