Evidence map›Paper›PMID 33957100›Full record

ArticleChest2021

Characterization of Aerosol Generation During Various Intensities of Exercise.

Pavol Sajgalik, Andres Garzona-Navas, Ibolya Csécs, J Wells Askew, Francisco Lopez-Jimenez, Alexander S Niven, Bruce D Johnson, Thomas G Allison

Abstract read
In one paragraph

Article in Chest, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Pavol SajgalikDepartment of Cardiovascular Medicine, Extreme Physiology Laboratory, Mayo Clinic, Rochester, MN.
Andres Garzona-NavasDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Ibolya CsécsDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
J Wells AskewDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Francisco Lopez-JimenezDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Alexander S NivenDepartment of Medicine, Division of Pulmonary, Critical Care, and Sleep Medicine, Mayo Clinic, Rochester, MN.
Bruce D JohnsonDepartment of Cardiovascular Medicine, Extreme Physiology Laboratory, Mayo Clinic, Rochester, MN; Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN.
Thomas G AllisonDepartment of Cardiovascular Medicine, Mayo Clinic, Rochester, MN. Electronic address: allison.thomas@mayo.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCharacterization of aerosol generation during exercise can inform the development of safety recommendations in the face of COVID-19. RESEARCH QUESTION: Does exercise at various intensities produce aerosols in significant quantities? STUDY DESIGN AND

methodsIn this experimental study, subjects were eight healthy volunteers (six men, two women) who were 20 to 63 years old. The 20-minute test protocol of 5 minutes rest, four 3-minute stages of exercise at 25%, 50%, 75%, and 100% of age-predicted heart rate reserve, and 3 minutes active recovery was performed in a clean, controlled environment. Aerosols were measured by four particle counters that were place to surround the subject.

resultsAge averaged 41 ± 14 years. Peak heart rate was 173 ± 17 beat/min (97% predicted); peak maximal oxygen uptake was 33.9 ± 7.5 mL/kg/min; and peak respiratory exchange ratio was 1.22 ± 0.10. Maximal ventilation averaged 120 ± 23 L/min, while cumulative ventilation reached 990 ± 192 L. Concentrations increased exponentially from start to 20 minutes (geometric mean ± geometric SD particles/liter): Fluke >0.3 μm = 66 ± 1.8 → 1605 ± 3.8; 0.3-1.0 μm = 35 ± 2.2 → 1095 ± 4.6; Fluke 1.0-5.0 μm = 21 ± 2.0 → 358 ± 2.3; P-Trak anterior = 637 ± 2.3 → 5148 ± 3.0; P-Trak side = 708 ± 2.7 → 6844 ± 2.7; P-Track back = 519 ± 3.1 → 5853 ± 2.8. All increases were significant at a probability value of <.05. Exercise at or above 50% of predicted heart rate reserve showed statistically significant increases in aerosol concentration.

interpretationOur data suggest exercise testing is an aerosol-generating procedure and, by extension, other activities that involve exercise intensities at or above 50% of predicted heart rate reserve. Results can guide recommendations for safety of exercise testing and other indoor exercise activities.

Indexed as

AdultAerosolsCOVID-19ExerciseExercise TestExhalationFemaleHealthy VolunteersHumansLungMaleMiddle AgedRespiratory Function TestsSARS-CoV-2Young AdultAerosolsaerosolexerciseexercise testing

Identifiers

PMID33957100
PMCPMC8473677

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.