ArticlePLoS computational biology2021
Modelling optimal vaccination strategy for SARS-CoV-2 in the UK.
Article in PLoS computational biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 111 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
111 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Predictive models for health outcomes due to SARS-CoV-2, including the effect of vaccination: a systematic review.Systematic reviews · 2024Pooled it
- The impact of risk prioritization in COVID-19 vaccination in Belgium on hospital and intensive care unit admissions.European journal of public health · 2026Article
- Article
- SIMPLICITY is an agent-based, multi-scale mathematical model to study SARS-CoV-2 intra- and between-host evolution.Communications biology · 2026Article
- Equity considerations in COVID-19 vaccine allocation modelling: a methodological study.Interface focus · 2025Review
- Understanding Nash epidemics.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Evaluating the effectiveness of vaccination campaigns: Insights from unvaccinated mortality data.Infectious Disease Modelling · 2025Article
- Vaccination strategies for different contact patterns: weighing epidemiological against economic outcomes.International journal of health economics and management · 2025Article
- Assessing the Economic Benefit of Mass COVID-19 Vaccination Program in Iran: A Real-World Modeling Study.International journal of health policy and management · 2025Article
- Learning from the COVID-19 pandemic: A systematic review of mathematical vaccine prioritization models.Infectious Disease Modelling · 2024Review
- Quantifying age-specific household contacts in Aotearoa New Zealand for infectious disease modelling.Royal Society open science · 2024Article
- Prioritising older individuals for COVID-19 booster vaccination leads to optimal public health outcomes in a range of socio-economic settings.PLoS computational biology · 2024Article
- When should lockdown be implemented? Devising cost-effective strategies for managing epidemics amid vaccine uncertainty.PLoS computational biology · 2024Article
- Epidemiological and health economic implications of symptom propagation in respiratory pathogens: A mathematical modelling investigation.PLoS computational biology · 2024Article
- Learning from the COVID-19 pandemic: a systematic review of mathematical vaccine prioritization models.medRxiv : the preprint server for health sciences · 2024Article
- An Epidemic Model with Infection Age and Vaccination Age Structure.Infectious disease reports · 2024Article
- Modeling geographic vaccination strategies for COVID-19 in Norway.PLoS computational biology · 2024Article
- Evaluation of vaccine rollout strategies for emerging infectious diseases: A model-based approach including protection attitudes.Infectious Disease Modelling · 2023Article
- Evaluating the COVID-19 vaccination program in Japan, 2021 using the counterfactual reproduction number.Scientific reports · 2023Article
- Rational social distancing policy during epidemics with limited healthcare capacity.PLoS computational biology · 2023Article
51 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
The COVID-19 outbreak has highlighted our vulnerability to novel infections. Faced with this threat and no effective treatment, in line with many other countries, the UK adopted enforced social distancing (lockdown) to reduce transmission-successfully reducing the reproductive number R below one. However, given the large pool of susceptible individuals that remain, complete relaxation of controls is likely to generate a substantial further outbreak. Vaccination remains the only foreseeable means of both containing the infection and returning to normal interactions and behaviour. Here, we consider the optimal targeting of vaccination within the UK, with the aim of minimising future deaths or quality adjusted life year (QALY) losses. We show that, for a range of assumptions on the action and efficacy of the vaccine, targeting older age groups first is optimal and may be sufficient to stem the epidemic if the vaccine prevents transmission as well as disease.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.