ArticlePLoS biology2021
An update to Hippocampome.org by integrating single-cell phenotypes with circuit function in vivo.
Article in PLoS biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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Who cites it
27 citing papers in PubMed.
- Hippocampome.org, a resource for subicular neuron types and beyond.bioRxiv : the preprint server for biology · 2025Article
- Episodic-like memory in a simulation of cuttlefish behavior.Scientific reports · 2025Article
- Synaptic proteome diversity is shaped by the levels of glutamate receptors and their regulatory proteins.Nature communications · 2025Article
- Human iPSC-Derived Mononuclear Phagocytes Improve Cognition and Neural Health across Multiple Mouse Models of Aging and Alzheimer's Disease.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Organization and Community Usage of a Neuron Type Circuitry Knowledge Base of the Hippocampal Formation.Biomedicines · 2025Article
- Episodic-Like Memory in a Simulation of Cuttlefish Behavior.bioRxiv : the preprint server for biology · 2025Article
- Biologically-informed excitatory and inhibitory ratio for robust spiking neural network training.Scientific reports · 2025Article
- Article
- Formation and retrieval of cell assemblies in a biologically realistic spiking neural network model of area CA3 in the mouse hippocampus.Journal of computational neuroscience · 2024Article
- Community-based reconstruction and simulation of a full-scale model of the rat hippocampus CA1 region.PLoS biology · 2024Article
- A Continuous Attractor Model with Realistic Neural and Synaptic Properties Quantitatively Reproduces Grid Cell Physiology.International journal of molecular sciences · 2024Article
- A Continuous Attractor Model with Realistic Neural and Synaptic Properties Quantitatively Reproduces Grid Cell Physiology.bioRxiv : the preprint server for biology · 2024Article
- Formation and Retrieval of Cell Assemblies in a Biologically Realistic Spiking Neural Network Model of Area CA3 in the Mouse Hippocampus.bioRxiv : the preprint server for biology · 2024Article
- Building a mathematical model of the brain.eLife · 2024Article
- Article
- Waveform-based classification of dentate spikes.Scientific reports · 2024Article
- Hippocampome.org v2.0: a knowledge base enabling data-driven spiking neural network simulations of rodent hippocampal circuits.bioRxiv : the preprint server for biology · 2024Article
- Waveform-based classification of dentate spikes.bioRxiv : the preprint server for biology · 2023Article
- Hippocampal GABAergic interneurons and memory.Neuron · 2023Review
- Robust Resting-State Dynamics in a Large-Scale Spiking Neural Network Model of Area CA3 in the Mouse Hippocampus.Cognitive computation · 2023Article
Corrections and comments
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Authors and funding
11 authors.
Funding
Abstract
Understanding brain operation demands linking basic behavioral traits to cell-type specific dynamics of different brain-wide subcircuits. This requires a system to classify the basic operational modes of neurons and circuits. Single-cell phenotyping of firing behavior during ongoing oscillations in vivo has provided a large body of evidence on entorhinal-hippocampal function, but data are dispersed and diverse. Here, we mined literature to search for information regarding the phase-timing dynamics of over 100 hippocampal/entorhinal neuron types defined in Hippocampome.org. We identified missing and unresolved pieces of knowledge (e.g., the preferred theta phase for a specific neuron type) and complemented the dataset with our own new data. By confronting the effect of brain state and recording methods, we highlight the equivalences and differences across conditions and offer a number of novel observations. We show how a heuristic approach based on oscillatory features of morphologically identified neurons can aid in classifying extracellular recordings of single cells and discuss future opportunities and challenges towards integrating single-cell phenotypes with circuit function.
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