Evidence map›Paper›PMID 33956178›Full record

ArticleEuropean radiology2021

Proposing a deep learning-based method for improving the diagnostic certainty of pulmonary nodules in CT scan of chest.

Ya-Wen Wang, Jian-Wei Wang, Shou-Xin Yang, Lin-Lin Qi, Hao-Liang Lin, Zhen Zhou, Yi-Zhou Yu

Abstract read
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Article in European radiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Article
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  5. The effectiveness of deep learning model in differentiating benign and malignant pulmonary nodules on spiral CT.Technology and health care : official journal of the European Society for Engineering and Medicine · 2024
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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ya-Wen WangDepartment of Diagnostic Radiology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Jian-Wei WangDepartment of Diagnostic Radiology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. dr_jianweiwang@163.com.ORCID http://orcid.org/0000-0002-9511-0952
Shou-Xin YangDepartment of Diagnostic Radiology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Lin-Lin QiDepartment of Diagnostic Radiology, National Cancer Center/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.
Hao-Liang LinDeepwise AI Lab, Beijing, China.
Zhen ZhouDeepwise AI Lab, Beijing, China.
Yi-Zhou YuDeepwise AI Lab, Beijing, China.

Funding

Medical and Health Science and Technology Innovation Project of Chinese Academy of Medical Sciences Grant No. 2018-I2M-AI-013the National Natural Science Foundation of China Grant No. 81971616
6 · The paper itself

Abstract

objectiveTo compare the performance of a deep learning (DL)-based method for diagnosing pulmonary nodules compared with radiologists' diagnostic approach in computed tomography (CT) of the chest. MATERIALS AND

methodsA total of 150 pathologically confirmed pulmonary nodules (60% malignant) assessed and reported by radiologists were included. CT images were processed by the proposed DL-based method to generate the probability of malignancy (0-100%), and the nodules were divided into the groups of benign (0-39.9%), indeterminate (40.0-59.9%), and malignant (60.0-100%). Taking the pathological results as the gold standard, we compared the diagnostic performance of the proposed DL-based method with the radiologists' diagnostic approach using the McNemar-Bowker test.

resultsThere was a statistically significant difference between the diagnosis results of the proposed DL-based method and the radiologists' diagnostic approach (p < 0.001). Moreover, there was no statistically significant difference in the composition of the diagnosis results between the proposed DL-based method and the radiologists' diagnostic approach (all p > 0.05). The difference in diagnostic accuracy between the proposed DL-based method (70%) and radiologists' diagnostic performance (64%) was not statistically significant (p = 0.243).

conclusionsThe proposed DL-based method achieved an accuracy comparable with the radiologists' diagnostic approach in clinical practice. Furthermore, its advantage in improving diagnostic certainty may raise the radiologists' confidence in diagnosing pulmonary nodules and may help clinical management. Therefore, the proposed DL-based method showed great potential in a certain clinical application. KEY POINTS: • Deep learning-based method for diagnosing the pulmonary nodules in computed tomography provides a higher diagnostic certainty.

Indexed as

Deep LearningLung NeoplasmsMultiple Pulmonary NodulesSolitary Pulmonary NoduleHumansTomography, X-Ray ComputedDeep learningDiagnosis, computer-assistedSolitary pulmonary noduleTomography, X-ray computed

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.