ArticleMolecular biology and evolution2021
Population Structure Limits Parallel Evolution in Sticklebacks.
Article in Molecular biology and evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed.
- Multiple modes of selection underlie repeated and human-mediated adaptation in a formerly migratory fish.Molecular biology and evolution · 2026Article
- Estimating Recent and Historical Effective Population Size of Marine and Freshwater Sticklebacks.Molecular ecology · 2025Article
- Rate of de novo mutations in the three-spined stickleback.Heredity · 2025Article
- The interplay between epigenomic and transcriptomic variation during ecotype divergence in stickleback.BMC biology · 2025Article
- Sex chromosome turnover in hybridizing stickleback lineages.Evolution letters · 2024Article
- Improved assembly of the Pungitius pungitius reference genome.G3 (Bethesda, Md.) · 2024Article
- Parallel evolution despite low genetic diversity in three-spined sticklebacks.Proceedings. Biological sciences · 2024Article
- Variable parallelism in the genomic basis of age at maturity across spatial scales in Atlantic Salmon.Ecology and evolution · 2024Article
- Anti-predator defences are linked with high levels of genetic differentiation in frogs.Proceedings. Biological sciences · 2024Article
- Variable Craniofacial Shape and Development among Multiple Cave-Adapted Populations ofIntegrative organismal biology (Oxford, England) · 2024Article
- De Novo Mutation Rates in Sticklebacks.Molecular biology and evolution · 2023Article
- Host habitat rather than evolutionary history explains gut microbiome diversity in sympatric stickleback species.Frontiers in microbiology · 2023Article
- The phoenix hypothesis of speciation.Proceedings. Biological sciences · 2022Article
- Relaxed risk of predation drives parallel evolution of stickleback behavior.Evolution; international journal of organic evolution · 2022Article
- Article
- Article
- Age-dependent genetic architecture across ontogeny of body size in sticklebacks.Proceedings. Biological sciences · 2022Article
- The genetics of adaptation in freshwater Eurasian shad (Ecology and evolution · 2022Article
- Threespine Stickleback: A Model System For Evolutionary Genomics.Annual review of genomics and human genetics · 2021Review
- Adaptive Divergence under Gene Flow along an Environmental Gradient in Two Coexisting Stickleback Species.Genes · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Population genetic theory predicts that small effective population sizes (Ne) and restricted gene flow limit the potential for local adaptation. In particular, the probability of evolving similar phenotypes based on shared genetic mechanisms (i.e., parallel evolution), is expected to be reduced. We tested these predictions in a comparative genomic study of two ecologically similar and geographically codistributed stickleback species (viz. Gasterosteus aculeatus and Pungitius pungitius). We found that P. pungitius harbors less genetic diversity and exhibits higher levels of genetic differentiation and isolation-by-distance than G. aculeatus. Conversely, G. aculeatus exhibits a stronger degree of genetic parallelism across freshwater populations than P. pungitius: 2,996 versus 379 single nucleotide polymorphisms located within 26 versus 9 genomic regions show evidence of selection in multiple freshwater populations of G. aculeatus and P. pungitius, respectively. Most regions involved in parallel evolution in G. aculeatus showed increased levels of divergence, suggestive of selection on ancient haplotypes. In contrast, haplotypes involved in freshwater adaptation in P. pungitius were younger. In accordance with theory, the results suggest that connectivity and genetic drift play crucial roles in determining the levels and geographic distribution of standing genetic variation, providing evidence that population subdivision limits local adaptation and therefore also the likelihood of parallel evolution.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.