Evidence map›Paper›PMID 33955843›Full record

ArticleJMIR research protocols2021

Influence of Stress, Gender, and Minority Status on Cardiovascular Disease Risk in the Hispanic/Latino Community: Protocol for a Longitudinal Observational Cohort Study.

Tonia Poteat, Linda C Gallo, Audrey Harkness, Carmen R Isasi, Phoenix Matthews, Neil Schneiderman, Bharat Thyagarajan, Martha L Daviglus, Daniela Sotres-Alvarez, Krista M Perreira

Open access · goldAbstract read
In one paragraph

Article in JMIR research protocols, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Article
  6. Article
  7. Psychosocial and Sociodemographic Determinants Related to Chronic Diseases in Immigrants Residing in Spain.International journal of environmental research and public health · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 7 institutions in 1 country.

Tonia PoteatDepartment of Social Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0001-6541-3787
Linda C GalloDepartment of Psychology, San Diego State University, San Diego, CA, United States.ORCID https://orcid.org/0000-0002-3678-5888
Audrey HarknessDepartment of Public Health Sciences, University of Miami, Miami, FL, United States.ORCID https://orcid.org/0000-0003-2290-9904
Carmen R IsasiDepartment of Epidemiology and Population Health, Albert Einstein College of Medicine, New York, NY, United States.ORCID https://orcid.org/0000-0003-2700-9593
Phoenix MatthewsDepartment of Population Health Nursing Science, University of Illinois Chicago, Chicago, IL, United States.ORCID https://orcid.org/0000-0002-0074-681X
Neil SchneidermanDepartment of Psychology, University of Miami, Miami, FL, United States.ORCID https://orcid.org/0000-0002-7982-068X
Bharat ThyagarajanDepartment of Laboratory Medicine and Pathology, University of Minnesota, Minneapolis, MN, United States.ORCID https://orcid.org/0000-0001-6968-6985
Martha L DaviglusInstitute for Minority Health Research, University of Illinois College of Medicine, Chicago, IL, United States.ORCID https://orcid.org/0000-0002-6791-8727
Daniela Sotres-AlvarezDepartment of Biostatistics, University of North Carolina at Chapel Hill, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0002-3226-6140
Krista M PerreiraDepartment of Social Medicine, University of North Carolina School of Medicine, Chapel Hill, NC, United States.ORCID https://orcid.org/0000-0003-2906-0261
University of North Carolina at Chapel Hill · USUniversity of Miami · USAlbert Einstein College of Medicine · USIllinois College · USSan Diego State University · USUniversity of Illinois Chicago · USUniversity of Minnesota · US

Funding

Stable Isotope and Metabolomics CoreP60DK020541 · NIDDK · YESHIVA UNIVERSITY · PI PESSIN, JEFFREY E. · 1986 to 2014
$29.8M
Translational Research CoreP30DK020541 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI STREAMSON C CHUA · 2015 to 2026
$27.7M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
New York Regional Center for Diabetes Translation Research - Translational Intervention Methodology CoreP30DK111022 · NIDDK · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI JEFFREY GONZALEZ · 2016 to 2026
$7.8M
Training Program for Scientists Conducting Research to Reduce HIV Health DisparitR25MH067127 · NIMH · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Emily A Arnold, Torsten Brian Neilands · 2003 to 2026
$5.4M
Cardiovascular Health of Sexual and Gender Minorities in the Hispanic Community Health Study/Study of Latinos (SGM HCHS/SOL)R01HL149778 · NHLBI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI PERREIRA, KRISTA M, POTEAT, TONIA C · 2020 to 2024
$3.5M
Thalassemia Clinical Research Network, CanadaU01HL065233 · NHLBI · UNIVERSITY HEALTH NETWORK · PI OLIVIERI, NANCY F · 2000 to 2009
$2.6M
GENETIC ARCHITECTURE OF PLASMA T-PA AND PAI-1R01HL065234 · NHLBI · VANDERBILT UNIVERSITY · PI MOORE, JASON H. · 2000 to 2004
$1.7M
HISPANIC COMMUNITY HEALTH STUDY-268065233N01HC065233 · HC · COORDINATING CENTER · PI CHAMBLESS, LLOYD E · 2006 to 2006
–
NHLBI NIH HHS N01 HC065233NHLBI NIH HHS N01 HC065234NHLBI NIH HHS N01 HC065235NHLBI NIH HHS N01 HC065236NHLBI NIH HHS N01 HC065237NHLBI NIH HHS R01 HL149778NICHD NIH HHS P2C HD050924NIDDK NIH HHS P30 DK020541NIDDK NIH HHS P30 DK111022NIDDK NIH HHS P60 DK020541NIMH NIH HHS R25 MH067127
6 · The paper itself

Abstract

backgroundHispanic/Latino sexual and gender minorities (SGM) are the fastest growing ethnic group of SGM in the United States. Cardiovascular disease (CVD) is a leading cause of morbidity and mortality among Hispanics/Latinos. SGM inequities in CVD risk have been identified as early as young adulthood, and minority stress has been identified as a potential mediator. Yet, the small number of ethnic or racial minority participants in SGM studies have precluded the examination of the intersections of sexual orientation, gender identity, and race and ethnicity.

objectiveMinority stress models conceptualize relationships between stressors in minority groups and health outcomes. In this study, we will (1) examine the influence of sexual orientation and gender identity on CVD risk among all Hispanic Community Health Study/Study of Latinos (HCHS/SOL) participants at visit 3 (2021-2024; N~9300); (2) model pathways from sexual orientation and gender identity to CVD risk through stigma, discrimination, and stress in a 1:2 matched subcohort of SGM and non-SGM participants at visit 3 (n~1680); and (3) examine the influence of resilience factors on sexual orientation or gender identity and CVD risk relationships among subcohort participants at visit 3 (n~1680).

methodsThis study will leverage existing data from the parent HCHS/SOL study (collected since 2008) while collecting new data on sexual orientation, gender identity, stigma, discrimination, stress, coping, social support, and CVD risk. Data analysis will follow the SGM minority stress model, which states that excess stigma against SGM populations leads to minority stress that increases CVD risk. In this model, coping and social support serve as resilience factors that can mitigate the impact of minority stress on CVD risk. Cross-sectional and longitudinal regression models as well as structural equation models will be used to test these relationships.

resultsThis study was funded by the National Heart, Lung, and Blood Institute in March 2020. Recruitment is scheduled to begin in the first quarter of 2021 and continue through 2024.

conclusionsUnderstanding the influence of stigma-induced stress on CVD risk among Hispanic/Latino SGM has significant implications for the development of culturally specific CVD risk reduction strategies. Study findings will be used to build on identified Hispanic/Latino cultural strengths to inform adaptation and testing of family and community acceptance interventions. INTERNATIONAL REGISTERED REPORT IDENTIFIER (IRRID): PRR1-10.2196/28997.

Indexed as

bisexualcardiovascular diseasegayHispanicintersexLatinolesbianminority stresssexual and gender minoritiestransgender

Identifiers

PMID33955843
PMCPMC8138714
OpenAlexW3158715832

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.