Evidence map›Paper›PMID 33955833›Full record

ArticleEpidemiology and infection2021

A cluster of Shiga Toxin-producing

Lukeki Kaindama, Claire Jenkins, Heather Aird, Frieda Jorgensen, Kelly Stoker, Lisa Byrne

Open access · goldAbstract read
In one paragraph

Article in Epidemiology and infection, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
  2. Mind the gap! TypingMicrobial genomics · 2026
    Article
  3. No evidence of multidrug-resistantMicrobiology spectrum · 2025
    Observational
  4. Article
  5. Review
  6. Review
  7. Article
  8. Cross-sectoral genomic surveillance reveals a lack of insight in sources of human infections with Shiga toxin-producingEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  9. Review
  10. Raw meat-based diet for pets: a neglected source of human exposure toEuro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Article
  11. Article
  12. Article
  13. The epidemiology of Shiga toxin-producingEpidemiology and infection · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Lukeki KaindamaNational Infection Service, Public Health England, 61 Colindale Avenue, LondonNW9 5HT, UK.
Claire JenkinsNational Infection Service, Public Health England, 61 Colindale Avenue, LondonNW9 5HT, UK.ORCID 0000-0001-8600-9169
Heather AirdFood Water and Environmental Microbiology Services, Public Health England, YorkYO41 ILZ, UK.
Frieda JorgensenFood Water and Environmental Microbiology Services, Public Health England, SalisburySP4 0JG, UK.
Kelly StokerNorth East Public Health England Centre, Public Health England, Newcastle upon TyneNE1 4WH, UK.
Lisa ByrneNational Infection Service, Public Health England, 61 Colindale Avenue, LondonNW9 5HT, UK.ORCID 0000-0001-5320-2085
Public Health England · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In August 2017, a cluster of four persons infected with genetically related strains of Shiga toxin-producing Escherichia coli (STEC) O157:H7 was identified. These strains possessed the Shiga toxin (stx) subtype stx2a, a toxin type known to be associated with severe clinical outcome. One person died after developing haemolytic uraemic syndrome. Interviews with cases revealed that three of the cases had been exposed to dogs fed on a raw meat-based diet (RMBD), specifically tripe. In two cases, the tripe had been purchased from the same supplier. Sampling and microbiological screening of raw pet food was undertaken and indicated the presence of STEC in the products. STEC was isolated from one sample of raw tripe but was different from the strain causing illness in humans. Nevertheless, the detection of STEC in the tripe provided evidence that raw pet food was a potential source of human STEC infection during this outbreak. This adds to the evidence of raw pet food as a risk factor for zoonotic transmission of gastrointestinal pathogens, which is widely accepted for Salmonella, Listeria and Campylobacter spp. Feeding RMBD to companion animals has recently increased in popularity due to the belief that they provide health benefits to animals. Although still rare, an increase in STEC cases reporting exposure to RMBDs was detected in 2017. There has also been an increased frequency of raw pet food incidents in 2017, suggesting an increasing trend in potential risk to humans from raw pet food. Recommendations to reduce the risk of infection included improved awareness of risk and promotion of good hygiene practices among the public when handling raw pet food.

Indexed as

PetsAnimalsDietDisease OutbreaksDogsEscherichia coli InfectionsEscherichia coli O157Food HandlingFood MicrobiologyHemolytic-Uremic SyndromeHumansMeatRaw FoodsShiga ToxinZoonosesShiga ToxinOne healthoutbreakraw pet foodShiga toxin-producing Escherichia coli

Identifiers

PMID33955833
PMCPMC8161292
OpenAlexW3158774726

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.