Evidence map›Paper›PMID 33955355›Full record

ArticleeLife2021

Endogenous p53 expression in human and mouse is not regulated by its 3'UTR.

Sibylle Mitschka, Christine Mayr

Abstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Review
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  11. Article
  12. Context-Dependent Function of Long Noncoding RNAMolecular and cellular biology · 2022
    Article
  13. Review
  14. Article
  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sibylle MitschkaCancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, United States.
Christine MayrCancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, United States.ORCID 0000-0002-7084-7608

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
3'UTR-mediated protein-protein interactions determine protein functionsDP1GM123454 · NIGMS · SLOAN-KETTERING INST CAN RESEARCH · PI MAYR, CHRISTINE · 2016 to 2020
$6.1M
NCI NIH HHS P30 CA008748NIGMS NIH HHS DP1 GM123454
6 · The paper itself

Abstract

The

Indexed as

Gene Expression Regulation3' Untranslated RegionsAnimalsCell LineCRISPR-Cas SystemsFemaleHumansMiceMice, Inbred C57BLProtein Processing, Post-TranslationalProteomicsTumor Suppressor Protein p533' Untranslated RegionsTP53 protein, humanTrp53 protein, mouseTumor Suppressor Protein p533′UTR knock-outcancer biologyCRISPR-mediated gene editingdeletion of endogenous 3′UTRsgeneticsgenomicshumanmousemouse modelPost-transcriptional gene regulationreporter assay

Identifiers

PMID33955355
PMCPMC8137139

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.