Evidence map›Paper›PMID 33955071›Full record

ArticleJournal of veterinary internal medicine2021

Urolithiasis in cats: Evaluation of trends in urolith composition and risk factors (2005-2018).

Lucy Kopecny, Carrie A Palm, Gilad Segev, Jennifer A Larsen, Jodi L Westropp

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
8.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it, 45 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Review
  4. Article
  5. The hitchhiker's guide to feline xanthinuria.Journal of feline medicine and surgery · 2026
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Lucy KopecnyDepartment of Veterinary Medicine and Epidemiology, University of California Davis, Davis, California, USA.ORCID https://orcid.org/0000-0002-6935-9463
Carrie A PalmDepartment of Veterinary Medicine and Epidemiology, University of California Davis, Davis, California, USA.ORCID https://orcid.org/0000-0003-1445-5113
Gilad SegevKoret School of Veterinary Medicine, The Robert H. Smith Faculty of Agriculture, Food and Environment, Hebrew University of Jerusalem, Rehovot, Israel.ORCID https://orcid.org/0000-0003-4714-3159
Jennifer A LarsenDepartment of Molecular Biosciences, University of California Davis, Davis, California, USA.
Jodi L WestroppDepartment of Veterinary Medicine and Epidemiology, University of California Davis, Davis, California, USA.ORCID https://orcid.org/0000-0003-1287-3979
University of California, Davis · USHebrew University of Jerusalem · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundUrolithiasis is an important upper and lower urinary tract disease in cats that results in morbidity and mortality.

objectiveTo describe trends in composition of uroliths in cats and evaluate risk factors related to age, breed, sex, urolith location, and bacterial urolith cultures. SAMPLE POPULATION: A total of 3940 uroliths and the cats from which they were obtained.

methodsThe database of the UC Davis Gerald V. Ling Urinary Stone Analysis Laboratory was searched for all urolith submissions from cats between January 2005 and December 2018. Mineral type, age, breed, sex, and urolith location and culture results were recorded. Trends were evaluated and variables compared to evaluate risk factors.

resultsA significant decrease in the proportion of calcium oxalate (CaOx)-containing uroliths occurred over time (P = .02), from 50.1% (204/407) of all submissions in 2005 to 37.7% (58/154) in 2018. In contrast, the proportion of struvite-containing uroliths increased significantly (P = .002), from 41.8% (170/407) in 2005 to 54.5% (84/154) in 2018. The proportion of CaOx-containing uroliths in the upper urinary tract was significantly higher compared to the proportion of other urolith types in the upper urinary tract. Urate-containing uroliths were the third most common type (361/3940, 9.2%). Overall, sex and age predispositions were similar to those reported previously. CONCLUSIONS AND CLINICAL IMPORTANCE: The decrease in the proportion of CaOx-containing uroliths and increase in the proportion of struvite-containing uroliths warrants investigation. Further education regarding the efficacy of medical dissolution of struvite-containing uroliths is recommended.

Indexed as

Cat DiseasesUrinary CalculiUrolithiasisAnimalsCatsMagnesium CompoundsPhosphatesRisk FactorsMagnesium CompoundsPhosphatescalcium oxalatefelinestruviteurateurolithiasis

Identifiers

PMID33955071
PMCPMC8162610
OpenAlexW3157927016

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.