Evidence map›Paper›PMID 33955065›Full record

ReviewActa paediatrica (Oslo, Norway : 1992)2021

The road to zero nosocomial infections in neonates-a narrative review.

Sophie J Jansen, Enrico Lopriore, Martha T van der Beek, Karin Ellen Veldkamp, Sylke J Steggerda, Vincent Bekker

Open access · bronzeAbstract readReview
In one paragraph

Review in Acta paediatrica (Oslo, Norway : 1992), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
3.3field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Microbial Infections and Antimicrobial Use in Neonates and Infants.Tropical medicine and infectious disease · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. The preventative effects ofFrontiers in microbiology · 2024
    Article
  9. Article
  10. Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Sophie J JansenDivision of Neonatology, Department of Pediatrics, Willem Alexander Children's Hospital - Leiden University Medical Center (LUMC), Leiden, The Netherlands.ORCID 0000-0002-2075-7487
Enrico LoprioreDivision of Neonatology, Department of Pediatrics, Willem Alexander Children's Hospital - Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Martha T van der BeekDepartment of Medical Microbiology, Leiden University Medical Center (LUMC, Leiden, The Netherlands.
Karin Ellen VeldkampDepartment of Medical Microbiology, Leiden University Medical Center (LUMC, Leiden, The Netherlands.
Sylke J SteggerdaDivision of Neonatology, Department of Pediatrics, Willem Alexander Children's Hospital - Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Vincent BekkerDivision of Neonatology, Department of Pediatrics, Willem Alexander Children's Hospital - Leiden University Medical Center (LUMC), Leiden, The Netherlands.
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimNosocomial infections (NI) in neonates are associated with prolonged hospitalisation, adverse neurodevelopmental outcome and high mortality. Over the past decade, numerous prevention strategies have resulted in significant reductions in NI rates. In this review, we aim to provide an overview of current NI rates from large, geographically defined cohorts.

methodsPubMed, Web of Science, EMBASE and Cochrane Library were searched for evidence regarding epidemiology and prevention of NI in neonates. Extracted studies were synthesised in a narrative form with experiential reflection.

resultsDespite the abundance of geographically defined incidence proportions, an epidemiological overview of NI is difficult to provide, given the lack of consensus definition for neonatal NI and different baseline populations being compared. Successful prevention efforts have focused on implementing evidence-based practices while eliminating outdated strategies. The most promising model for reduction in infection rates is based on quality improvement (QI) collaboratives and benchmarking, involving identification and implementation of best practices, selection of measurable outcomes and fostering a sense of community and transparency.

conclusionThe preventative rather than curative approach forms the new paradigm for reducing the burden of neonatal infections. Despite progress achieved, continued work towards improved prevention practices is required in the strive towards zero NIs.

Indexed as

Cross InfectionHumansIncidenceInfant, Newbornneonatesnosocomial infectionsquality improvement

Identifiers

PMID33955065
PMCPMC8359829
OpenAlexW3157699593

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.