Evidence map›Paper›PMID 33954817›Full record

ReviewAnnals of hematology2021

What is known about palliative care in adult patients with allogeneic stem cell transplantation (allo-SCT)?

Steffen T Simon, Anne Pralong, Michael Hallek, Christoph Scheid, Udo Holtick, Marco Herling

Open access · hybridAbstract readReview
In one paragraph

Review in Annals of hematology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Supportive Care of Hematopoietic Stem Cell Donors.Clinical hematology international · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 2 countries.

Steffen T Simon *Faculty of Medicine and Cologne University Hospital, Department of Palliative Medicine, University of Cologne, 50924, Cologne, Germany.
Anne Pralong *Faculty of Medicine and Cologne University Hospital, Department of Palliative Medicine, University of Cologne, 50924, Cologne, Germany. anne.pralong@uk-koeln.de.ORCID http://orcid.org/0000-0001-8201-2344
Michael HallekFaculty of Medicine and Cologne University Hospital, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf (CIO ABCD), University of Cologne, Cologne, Germany.
Christoph ScheidFaculty of Medicine and Cologne University Hospital, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf (CIO ABCD), University of Cologne, Cologne, Germany.
Udo HoltickFaculty of Medicine and Cologne University Hospital, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf (CIO ABCD), University of Cologne, Cologne, Germany.
Marco HerlingFaculty of Medicine and Cologne University Hospital, Center for Integrated Oncology Aachen-Bonn-Cologne-Duesseldorf (CIO ABCD), University of Cologne, Cologne, Germany.
University of Cologne · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients undergoing allogeneic stem cell transplantation (allo-SCT) are given a real chance of cure, but at the same time are confronted with a considerable risk of mortality and of severe long-term impediments. This narrative, non-systematic literature review aims to describe the supportive and palliative care needs of allo-SCT recipients, including long-term survivors or those relapsing or dying after transplantation. It also evaluates the feasibility and effectivity of integrating palliative care early in transplant procedures. In this appraisal of available literature, the main findings relate to symptoms like fatigue and psychological distress, which appear to be very common in the whole allo-SCT trajectory and might even persist many years post-transplantation. Chronic GvHD has a major negative impact on quality of life. Overall, there is a paucity of research on further issues in the context of allo-SCT, like the distress related to the frequently unpredictable post-transplant trajectory and prognosis, as well as the end-of-life phase. First randomized controlled results support the effectiveness of early integration of specialized palliative care expertise into transplant algorithms. Barriers to this implementation are discussed.

Indexed as

Hematopoietic Stem Cell TransplantationPalliative CareTransplantation, HomologousChronic DiseaseFatigueGraft vs Host DiseaseHumansPsychological DistressQuality of LifeAllogeneic transplantationPalliative medicineQuality of lifeStem cell transplantationSupportive care

Identifiers

PMID33954817
PMCPMC8116288
OpenAlexW3157681734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.