Evidence map›Paper›PMID 33954290›Full record

ArticleNeuroscience insights2021

Binge-Like Ethanol Drinking Increases

Cassandre Coles, Amy W Lasek

Open access · goldAbstract read
In one paragraph

Article in Neuroscience insights, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.3field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Cassandre ColesCenter for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-9379-6209
Amy W LasekCenter for Alcohol Research in Epigenetics, Department of Psychiatry, University of Illinois at Chicago, Chicago, IL, USA.ORCID https://orcid.org/0000-0002-7099-2442
University of Illinois Chicago · US

Funding

Pilot Project Program P50AA022538 · NIAAA · UNIVERSITY OF ILLINOIS AT CHICAGO · PI SUBHASH C. PANDEY · 2015 to 2026
$21.3M
Regulation of Excessive Alcohol Consumption by the Lmo-Alk AxisU01AA020912 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI Amy Wolven Lasek · 2011 to 2026
$5.4M
NIAAA NIH HHS P50 AA022538NIAAA NIH HHS U01 AA020912
6 · The paper itself

Abstract

Alcohol use disorder is associated with pathophysiological changes in the dopaminergic system. Orthodenticle homeobox 2 (OTX2) is a transcription factor important for the development of dopaminergic neurons residing in the ventral tegmental area (VTA), a critical region of the brain involved in drug reinforcement. Previous studies have demonstrated that ethanol exposure during embryonic development reduces

Indexed as

Alcohol use disorderdopamineethanolMdkmouseOtx2Wnt1

Identifiers

PMID33954290
PMCPMC8058803
OpenAlexW3156089353

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.